Tegaserod
- CAS No.
- 145158-71-0
- Chemical Name:
- Tegaserod
- Synonyms
- TEGASEROD;Tegaserode;Tegaserod USP/EP/BP;2-[(5-methoxy-1h-indol-3-yl)methylene]-n-pentylhydrazine-carboximidamide;Hydrazinecarboximidamide, 2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pentyl-;(E)-2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentylhydrazine-1-carboximidamide;Tegaserod D10Q: What is Tegaserod D10 Q: What is the CAS Number of Tegaserod D10;Tegaserod 13CD3Q: What is Tegaserod 13CD3 Q: What is the CAS Number of Tegaserod 13CD3;Tegaserod D11 (Major-D10)Q: What is Tegaserod D11 (Major-D10) Q: What is the CAS Number of Tegaserod D11 (Major-D10)
- CBNumber:
- CB0225423
- Molecular Formula:
- C16H23N5O
- Molecular Weight:
- 301.39
- MOL File:
- 145158-71-0.mol
- Modify Date:
- 2024/7/2 8:54:57
| Melting point | 155° |
|---|---|
| Boiling point | 470.6±48.0 °C(Predicted) |
| Density | 1.18 |
| storage temp. | 2-8°C |
| form | Solid |
| pka | 15.81±0.30(Predicted) |
| color | White to off-white |
| CAS DataBase Reference | 145158-71-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xi |
|---|---|
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 36/37-36-26 |
Tegaserod Chemical Properties,Uses,Production
Uses
Treatment of gastrointestinal motility disorders (selective serotonin 5HT4antagonist).
Indications
Tegaserod (Zelnorm) is serotonin-4 (5-HT4) receptor agonists that stimulate GI motility.
Clinical Use
Tegaserod is being developed as a treatment for constipation- predominant irritable bowel syndrome (IBS). Within the first week, patients treated with tegaserod had significant improvements in abdominal pain and discomfort, constipation, and overall well-being. Efficacy was maintained throughout the treatment period. Tegaserod also demonstrated significant improvements in the three bowel-related assessments (stool frequency, stool consistency, and straining) within the first week, and these improvements were sustained throughout the treatment period. The most common adverse events reported thus far are headache and diarrhea.
Tegaserod Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Viyash Life Sciences Pvt Ltd | +91-4023635052 +91-4023635052 | Telangana, India | 213 | 58 | Inquiry |
| Alembic Pharmaceuticals Limited | +91-2652280880 +91-2652280550 | Gujarat, India | 115 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29899 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49403 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-15319487004 | China | 2132 | 58 | Inquiry |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |