Sodium thiomethoxide
- CAS No.
- 5188-07-8
- Chemical Name:
- Sodium thiomethoxide
- Synonyms
- SODIUM METHANETHIOLATE;SODIUM METHYL MERCAPTIDE;METHYL MERCAPTAN SODIUM SALT;Sodium thiomethylate;Sodium methylthiolate;SODIUM METHYLMERCAPTAN;SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM);Sodium me;thioformate;methanethiolate
- CBNumber:
- CB1476576
- Molecular Formula:
- CH3NaS
- Molecular Weight:
- 70.09
- MOL File:
- 5188-07-8.mol
- Modify Date:
- 2024/8/1 10:49:18
| Density | 1.12[at 20℃] |
|---|---|
| vapor pressure | 29hPa at 25℃ |
| Flash point | 27°C |
| storage temp. | Flammables area |
| solubility | soluble in Water |
| form | Powder |
| color | White to off-white |
| Water Solubility | soluble |
| Merck | 14,5956 |
| BRN | 3592983 |
| InChI | InChI=1S/CH4S.Na/c1-2;/h2H,1H3;/q;+1/p-1 |
| InChIKey | RMBAVIFYHOYIFM-UHFFFAOYSA-M |
| SMILES | CS[Na] |
| LogP | -2.33 at 20℃ |
| CAS DataBase Reference | 5188-07-8(CAS DataBase Reference) |
| EPA Substance Registry System | Methanethiol, sodium salt (5188-07-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H226-H302-H314 | |||||||||
| Precautionary statements | P210-P280-P301+P312+P330-P301+P330+P331-P303+P361+P353-P305+P351+P338+P310 | |||||||||
| Hazard Codes | C,F | |||||||||
| Risk Statements | 31-34-20/21/22-11-35-25-10 | |||||||||
| Safety Statements | 26-36/37/39-45-16 | |||||||||
| RIDADR | UN 3263 8/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 1-34-10-13 | |||||||||
| HazardClass | 4.3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29309090 | |||||||||
| NFPA 704 |
|
Sodium thiomethoxide price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 71742 | Sodium methanethiolate technical, ≥90% (RT) | 5188-07-8 | 5G | ₹10359.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 71742 | Sodium methanethiolate technical, ≥90% (RT) | 5188-07-8 | 25G | ₹30721.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 281018 | Sodium thiomethoxide 95% | 5188-07-8 | 1G | ₹4384.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 516686 | Sodium thiomethoxide solution 21% in H2O | 5188-07-8 | 1L | ₹8162.05 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 281018 | Sodium thiomethoxide 95% | 5188-07-8 | 5G | ₹10770.88 | 2022-06-14 | Buy |
Sodium thiomethoxide Chemical Properties,Uses,Production
Description
Sodium methanethiolate or sodium thiomethoxide (CH3SNa, MeSNa) is the sodium conjugate base of methanethiol. This compound is commercially available as a white solid. Sodium Methanethiolate is used as a nucleophile in organic synthesis. This compound is also being used as a reagent to synthesize thiol-based suberoylanilide hydroxamic acid (SAHA) analogues, compounds that act as potent histone deacetylase inhibitors. It reacts with trifluoroacetic acid and water to produce the active form of sodium trifluoroacetate. The reaction mechanism is likely due to the formation of a bicyclic heterocycle that has been shown to be effective against a number of bacteria.
Chemical Properties
Very faint yellowish red clear liquid
Uses
Sodium thiomethoxide is a strong nucleophile used for the synthesis of methyl aryl sulfides from halo-arenes. Alkanethiolates are efficient reagents for SN2 dealkylation of esters and aryl ethers.
Reactivity Profile
Sodium thiomethoxide is a powerful nucleophile that can be used to prepare methylthioether and other organic compounds like ethyl bromide. Its hydrolysis in moist air produces methanethiol, which has a low odor threshold and a noxious fecal smell.
Purification Methods
Dissolve the salt (10g) in EtOH (10mL) and add Et2O (100mL). Cool and collect the precipitate, wash it with Et2O and dry it in a vacuum. It is a white powder which is very soluble in EtOH and H2O. [Billmann & Jensen Bull Soc Chim Fr 3 2318 1936, Beilstein 1 III 1212.]
Sodium thiomethoxide Preparation Products And Raw materials
Raw materials
Preparation Products
2-Aminoethylmethylsulfone hydrochloride
Simetryne
Prometryn
2-(METHYLTHIO)ETHANOL
2-(Methylthio)pyrazine
4,6-DICHLORO-2-(TRIFLUOROMETHYL)QUINOLINE
2-(METHYLTHIO)THIOPHENE
Ametryn
Methylthio acetaldoxime
5-(METHYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID
ETHYL METHANESULFONYLACETATE
4-Methylthio-2-butanone
Dimethyl sulfide
METHYL MERCAPTAN
Prairie Net Wettable Powder
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Global( 329)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Noble Molecular Research | +91 9717706044 | Uttar Pradesh, India | 85 | 58 | Inquiry |
| Orchev Pharma Pvt Ltd | +91-2812365732 +91-2812365731 | Gujarat, India | 7 | 58 | Inquiry |
| Aravali Pharma And Lifesciences | +91-9350857917 +91-9810502945 | New Delhi, India | 119 | 58 | Inquiry |
| Karvy Therapeutics Pvt Ltd | +91-9824044913 +91-9824044913 | Gujarat, India | 10 | 58 | Inquiry |
| Survival Technologies Pvt Ltd | +91 (22) 4212-8221 | New Delhi, India | 290 | 50 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Orchev Pharma Private Limited | 08048372600Ext 770 | Gujarat, India | 3 | 58 | Inquiry |
| Symax Laboratories | 08048951311 | Mallapur, India | 56 | 58 | Inquiry |
| Nischal Store | 08048361359Ext 900 | Delhi, India | 9 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Noble Molecular Research | 58 |
| Orchev Pharma Pvt Ltd | 58 |
| Aravali Pharma And Lifesciences | 58 |
| Karvy Therapeutics Pvt Ltd | 58 |
| Survival Technologies Pvt Ltd | 50 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Orchev Pharma Private Limited | 58 |
| Symax Laboratories | 58 |
| Nischal Store | 58 |
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Related Qustion
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5188-07-8(Sodium thiomethoxide)Related Search:
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SODIUM METHYL SULFIDE
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Sodium thiomethoxide solution
METHANETHIOL SODIUM SALT
Sodium methanethiolate, 21% aqueous solution
Sodium me
Sodium methionine
Sodium thiomethoxide, 15% in water
methanethiolate
SODIUM THIOMETHOXIDE, 21 VOL. % SOLN IN WATER, A PRODUCT OF ELF ATOCHEM (SMM)
Sodium methylthiolate
Sodium thiomethylate
SODIUM METHYLMERCAPTAN
METHYL MERCAPTAN SODIUM SALT
SODIUM METHANETHIOLATE
SODIUM METHYL MERCAPTIDE
High purity Sodium thiomethoxide
5188-07-8
5188-7-8
1201-10-8
1201108
CH3NaS
CH3SNa
Building Blocks
Na (Sodium) Compounds (excluding simple sodium salts)
Typical Metal Compounds
Classes of Metal Compounds
Sulfur Compounds
Thiol/Mercaptan Salts
Organic Building Blocks
Classes of Metal Compounds
Na (Sodium) Compounds (excluding simple sodium salts)
Typical Metal Compounds
API
Aliphatics
Sulfur & Selenium Compounds