Crystal Violet
- CAS No.
- 548-62-9
- Chemical Name:
- Crystal Violet
- Synonyms
- GENTIAN VIOLET;Methyl violet;304;gentian;BASIC VIOLET 3;METHYLROSANILINE;METHYLROSANILINE CHLORIDE;METHYL VIOLET 10B;methylviolett;Crystal violent
- CBNumber:
- CB2161846
- Molecular Formula:
- C25H30ClN3
- Molecular Weight:
- 407.99
- MOL File:
- 548-62-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/17 21:30:02
| Melting point | 205 °C (dec.) (lit.) |
|---|---|
| Boiling point | 560.86°C (rough estimate) |
| Density | 1.19 g/cm3 at 20 °C |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.6010 (estimate) |
| Flash point | 40 °C |
| storage temp. | room temp |
| solubility | water: soluble50g/L at 27°C |
| Colour Index | 42555 |
| pka | 9.4(at 25℃) |
| form | Solid |
| color | S. No.: 785 |
| PH Range | 0.8(yellow)-2.6(blue/violet) |
| Odor | Slight characteristic odor |
| PH | 2.5-3.5 (10g/l, H2O, 20℃) |
| Water Solubility | 16 g/L (25 ºC) |
| λmax | 590nm |
| Merck | 14,4395 |
| BRN | 4077708 |
| Stability | Stable. Incompatible with strong oxidizing agents, strong acids. Light-sensitive. Combustible. |
| Biological Applications | Detecting microorganisms; treating atopic dermatitis,dermatological diseases,28,skin wounds,lesions,hemorrhoids,1,multiple myeloma,Non-Hodgkin’s lymphoma,breast cancer,neurodegenerative diseases,onychomycosis; wound dressing |
| Major Application | Photoresists, lithographic printing plate, printed circuit board, inks, hair dyes, shampoo, drug screening method, bone cement preparation method, microorganisms, hemorrhoids, antifungal, antibacterial, antimalarial agent, dental application |
| InChIKey | ZXJXZNDDNMQXFV-UHFFFAOYSA-M |
| LogP | 1.172 at 25℃ |
| CAS DataBase Reference | 548-62-9(CAS DataBase Reference) |
| EPA Substance Registry System | Crystal violet (548-62-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |     GHS05,GHS07,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H318-H350-H410 | |||||||||
| Precautionary statements | P202-P273-P280-P301+P312-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn,N,T,C | |||||||||
| Risk Statements | 52/53-50/53-45-41-22-40-34-10-36/37/38-23/25-51/53-68 | |||||||||
| Safety Statements | 61-60-53-45-46-36/37/39-26-39-36/37-16-22 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | BO9000000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 32041300 | |||||||||
| Toxicity | LD50 orally in mice, rats: 1.2, 1.0 g/kg (Hodge) | |||||||||
| NFPA 704 |
|
Crystal Violet price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | V5265 | Crystal violet solution 1%, aqueous solution | 548-62-9 | 250ML | ₹6904.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | V5265 | Crystal violet solution 1%, aqueous solution | 548-62-9 | 500ML | ₹7792.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G2039 | Gentian Violet meets USP testing specifications | 548-62-9 | 25G | ₹4451.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G2039 | Gentian Violet meets USP testing specifications | 548-62-9 | 100G | ₹12032.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C6158 | Crystal Violet ACS reagent, ≥90.0% anhydrous basis | 548-62-9 | 50G | ₹7026.3 | 2022-06-14 | Buy |
Crystal Violet Chemical Properties,Uses,Production
Description
Crystal Violet is light sensitive. May react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release gaseous hydrogen.
Chemical Properties
dark green powder or crystals
Occurrence
Gentian is a fl owering perennial found in Europe and Asia.
Uses
Crystal Violet is used as an acid-base indicator, an alcohol denaturant, a biological stain, a textile dye and an indicator for copper salts. It is a component of gram staining in microorganisms and cell lines.
Preparation
It is manufactured through using N, N-dimethylaniline as raw materials, followed by condensation, addition, chlorination and other reactions. Alternatively, it can be synthesized through the reaction between Michler ketone and N, N-dimethylaniline reaction in the presence of phosphorus oxychloride, followed by azeotropic reaction with hydrochloric acid.
Recrystallization in hot water will generate compound containing nine crystal water molecules.
Essential oil composition
A number of bitter compounds present in gentian are primarily amarogentin (strongly bitter), gentiopricin (approximately 1.5% in fresh root), swertiamarin and gentiopricroside. The leaves and flowers contain mainly xanthones. Secoiridoids and flavonoids were also detected. In the phase of flowering, leaves are rich with compounds possessing C-glycoside structures while O-glycoside structures accumulate mainly before flowering.
General Description
It belongs to triamino-triphenylmethane synthetic dyes; alkaline. It is an important dye used in bacterial Gram stain. The mixed reagent of crystal violet chloride and iodine is known as gentian violet.
Air & Water Reactions
Insoluble in water.
Fire Hazard
Flash point data for Crystal Violet are not available, however, Crystal Violet is probably combustible.
Clinical Use
Gentian violet is variously known as hexamethyl-p-rosanilinechloride, crystal violet, methyl violet, and methylrosanilinechloride. It occurs as a green powder or greenflakes with a metallic sheen. The compound is soluble inwater (1:35) and alcohol (1:10) but insoluble in nonpolar organicsolvents. Gentian violet is available in vaginal suppositoriesfor the treatment of yeast infections. It is also used asa 1% to 3% solution for the treatment of ringworm and yeastinfections. Gentian violet has also been used orally as an anthelminticfor strongyloidiasis (threadworm) and oxyuriasis.
Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes, An experimental teratogen. Other experimental reproductive effects. A human sktn irritant. Human mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of NO, and Cl-.
Purification Methods
Crystallise the dye from water (20mL/g), the crystals being separated from the chilled solution by centrifugation, then wash them with chilled EtOH (solubility is 1g in 10 mL of hot EtOH) and diethyl ether and dry under vacuum. It is soluble in CHCl3 but insoluble in Et2O. The carbinol is precipitated from an aqueous solution of the dye-hydrochloride, using excess NaOH, then dissolve in HCl and recrystallise it from water as the chloride [UV and kinetics: Turgeon & La Mer J Am Chem Soc 74 5988 1952]. The carbinol base has m 195o (needles from EtOH). The diphthalate (blue and turns red in H2O) crystallises from H2O, m 153-154o(dec at 185-187o)[Chamberlain & Dull J Am Chem Soc 50 3089 1928]. [Beilstein 13 H 233, 13 IV 2284.]
Crystal Violet Preparation Products And Raw materials
Raw materials
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Arnish Laborates Pvt Ltd | +91 7208475595 | Maharashtra, India | 187 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Macsen Labs | +91-7296866111 +91-9309241616 | Rajasthan, India | 11 | 58 | Inquiry |
| Colorants Chem Pvt Ltd | +91-9890098067 +91-9890036907 | Mumbai, India | 200 | 58 | Inquiry |
| Unilex Colours and Chemicals Ltd | +91-9820430671 +91-9321169592 | Mumbai, India | 102 | 58 | Inquiry |
| Mehul Dye Chem Industries | +91 9824110851 | Gujarat, India | 29 | 58 | Inquiry |
| Jagson Colorchem Limited | +91-9879484214 +91-9879484214 | Gujarat, India | 318 | 58 | Inquiry |
| Amogh Chemicals Pvt Ltd | +91-9920471328 +91-9833649289 | Maharashtra, India | 170 | 58 | Inquiry |
| Merck Ltd | +91-2262109800 +91-2262109000 | Maharashtra, India | 272 | 58 | Inquiry |
| Satyawati Chemicals | +91-9890962629 +91-9890962629 | Maharashtra, India | 18 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Arnish Laborates Pvt Ltd | 58 |
| JSK Chemicals | 58 |
| Macsen Labs | 58 |
| Colorants Chem Pvt Ltd | 58 |
| Unilex Colours and Chemicals Ltd | 58 |
| Mehul Dye Chem Industries | 58 |
| Jagson Colorchem Limited | 58 |
| Amogh Chemicals Pvt Ltd | 58 |
| Merck Ltd | 58 |
| Satyawati Chemicals | 58 |
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