HC TOXIN

CAS No.: 83209-65-8

Chemical Name:: HC TOXIN

Synonyms: Toxin I;HC TOXIN;HC toxin I;Cyclo(aoe-Pro-Ala-ala);HC TOXIN FROM HELMINTHOSPORIUM CARBONUM;Cyclo[D-Pro-L-Ala-D-Ala-2-(6-oxo-6-oxiranylhexyl)-L-Gly-];CYCLO-(D-PRO-L-ALA-D-ALA-L-2-AMINO-8-OXO-9,10-EPOXYDECANOIC ACID);Cyclo[L-Ala-D-Ala-[(2S)-2-amino*-8-oxo-8-oxiranyloctanoyl]-D-Pro-];Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine);Cyclic(L-alanyl-D-alanyl-eta-oxo-L-alpha-aminooxiraneoctanoyl-D-prolyl)

CBNumber:: CB2460604

Molecular Formula:: C21H32N4O6

Molecular Weight:: 436.51

MOL File:: 83209-65-8.mol

MSDS File:: SDS

Modify Date:: 2024/7/2 8:55:03

Request For Quotation

HC TOXIN Properties

Boiling point	819.2±65.0 °C(Predicted)
Density	1.28±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 10 mg/ml; Methanol: 10 mg/ml
pka	13.33±0.70(Predicted)
form	lyophilized powder
color	Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H300

Precautionary statements

P264-P301+P310

Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

NFPA 704

	0
4		0

HC TOXIN price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	H7270	HC toxin from Helminthosporium carbonum lyophilized powder	83209-65-8	5MG	₹71196.03	2022-06-14	Buy

Product number	Packaging	Price	Buy
H7270	5MG	₹71196.03	Buy

HC TOXIN Chemical Properties,Uses,Production

Description

HC Toxin is a cell-permeable, reversible inhibitor of histone deacetylases (HDACs) (IC₅₀ = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate the expression of 15-lipoxygenase-1 in colorectal cancer cells and induce fetal hemoglobin in human primary erythroid cells. HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.

Uses

HC Toxin is an HDAC inhibitor. Cyclic tetrapeptide[1] fungal toxin selectively toxic to plants with susceptible host genotype (2)

Definition

ChEBI: A homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues.

HC TOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

HC TOXIN Suppliers

Global( 63)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-400-6206333 18521732826	China	25014	65	Inquiry
RD International Technology Co., Limited	18024082417	China	9155	58	Inquiry
TargetMol Chemicals Inc.	15002134094	China	28118	58	Inquiry
BOC Sciences		USA	0	65	Inquiry
Naturewill Biotechnology Co., Ltd.	18113192475 18113192475	China	5000	58	Inquiry
Guangzhou Yaoguang Technology Co., Ltd.	13020159086	China	487	58	Inquiry
Creative Enzymes	1-516-855-7709	United States	6057	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
Aladdin Scientific	58
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
RD International Technology Co., Limited	58
TargetMol Chemicals Inc.	58
BOC Sciences	65
Naturewill Biotechnology Co., Ltd.	58
Guangzhou Yaoguang Technology Co., Ltd.	58
Creative Enzymes	58

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HC TOXIN FROM HELMINTHOSPORIUM CARBONUM Cyclo[D-Pro-L-Ala-D-Ala-2-(6-oxo-6-oxiranylhexyl)-L-Gly-] Cyclo[L-Ala-D-Ala-[(2S)-2-amino*-8-oxo-8-oxiranyloctanoyl]-D-Pro-] HC toxin I Toxin I Cyclic(L-alanyl-D-alanyl-eta-oxo-L-alpha-aminooxiraneoctanoyl-D-prolyl) Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine) Cyclo(aoe-Pro-Ala-ala) Cyclo(L-alanyl-D-alanyl-(alphas,2S)-alpha-amino-eta-oxooxiraneoctanoyl-D-prolyl) Cyclo(L-alanyl-D-alanyl-8-oxiranyl-8-oxo-L-2-aminooctanoyl-D-prolyl), (S)- CYCLO-(D-PRO-L-ALA-D-ALA-L-2-AMINO-8-OXO-9,10-EPOXYDECANOIC ACID) HC TOXIN (3S,6R,9S,12R)-6,9-dimethyl-3-[6-[(2S)-oxiran-2-yl]-6-oxohexyl]-1,4,7,10-tetrazabicyclo[10.3.0]pentadecane-2,5,8,11-tetrone 83209-65-8 C21H32N4O6 Cell Signaling and Neuroscience Mold Toxins and Venoms