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Clindamycin palmitate hydrochloride

CAS No.: 25507-04-4

Chemical Name:: Clindamycin palmitate hydrochloride

Synonyms: Clindmycin;Cleocin Pediatric;Clindamycin Impurity 85;CLINDAMYCIN PALMITATE HCL;Clindamycin 2-Palmitate HCl;ClindaMycin PalMitate HCl USP;Clindamycin Hydrochloride Palmitate;Clindamycin palmitate hydrochloride;clindamycin2’-palmitatehydrochloride;Clindamycin Palmitate Hydrochloride (USP)

CBNumber:: CB3666368

Molecular Formula:: C34H64Cl2N2O6S

Molecular Weight:: 699.85

MOL File:: 25507-04-4.mol

Modify Date:: 2024/11/19 15:53:33

Request For Quotation

Clindamycin palmitate hydrochloride Properties

Melting point	141-143°C
storage temp.	-20°C Freezer, Under Inert Atmosphere
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
InChIKey	GTNDZRUWKHDICY-ZLNNALEKSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P264-P280-P305+P351+P338-P337+P313P

HS Code

2941906000

NFPA 704

	0
2		0

Clindamycin palmitate hydrochloride Chemical Properties,Uses,Production

Description

Clindamycin palmitate is a water-soluble prodrug form of the antibiotic clindamycin . It undergoes rapid hydrolysis in vivo to release active clindamycin. Formulations containing clindamycin palmitate have been used in the treatment of various bacterial infections.

Chemical Properties

White Solid

Uses

antibacterial (tuberculostatic)

General Description

Clindamycin palmitate hydrochloride (Cleocin Pediatric) isthe hydrochloride salt of the palmitic acid ester ofcleomycin. The ester bond is to the 2-hydroxyl group of thelincosamine sugar. The ester serves as a tasteless prodrugform of the antibiotic, which hydrolyzes to clindamycin inthe plasma. The salt form confers water solubility to theester, which is available as granules for reconstitution intoan oral solution for pediatric use. Although absorption of thepalmitate is slower than that of the free base, there is littledifference in overall bioavailability of the two preparations.Reconstituted solutions of the palmitate hydrochloride arestable for 2 weeks at room temperature. Such solutionsshould not be refrigerated because thickening occurs thatmakes the preparation difficult to pour.

Clindamycin palmitate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Butyldi-1-adamantylphosphine BENZOFURAZAN-5-CARBONYL CHLORIDE 8-Methyl-8-azabicyclo[3.2.1]octan-3-amine dihydrochloride 5-CHLORO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID 5-BROMO-2-(METHYLSULFONYL)PYRIMIDINE-4-CARBOXYLIC ACID

5-Bromo-2-(methylthio)pyrimidine-4-carboxylic acid 5-CHLORO-2-METHOXYPYRIMIDINE-4-CARBOXYLIC ACID METHYL 5-BROMO-2-(METHYLSULFANYL)-4-PYRIMIDINECARBOXYLATE, 97 5-(BROMOMETHYL)-2,1,3-BENZOXADIAZOLE 2-AMINO-4-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID

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Clindamycin palmitate hydrochloride Suppliers

Global( 198)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
LUPIN LTD	+91 124 4885000 / +91 124 3325000	New Delhi, India	191	58	Inquiry
AUROBINDO PHARMA LTD	+91 (40) 6672 1200	New Delhi, India	209	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6739	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6257	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6754	58	Inquiry
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	China	8806	58	Inquiry
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	China	12832	58	Inquiry
Hebei Kingfiner Technology Development Co.Ltd	+86-15532196582 +86-15373005021	China	3009	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +8618949832763	China	2986	55	Inquiry
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8618959220845	China	6383	58	Inquiry

Supplier	Advantage
LUPIN LTD	58
AUROBINDO PHARMA LTD	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
CLEARSYNTH LABS LTD.	58
Pharma Affiliates	58
Hebei Weibang Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Kingfiner Technology Development Co.Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	55
Xiamen AmoyChem Co., Ltd	58

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Clindmycin clindamycin2’-palmitatehydrochloride Methyl7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside2-hexadecanoatemonohydrochloride Clindamycin palmitate hydrochloride Clindamycin Palmitate Hydrochloride (500 mg) Clindamycin Palmitate Hydrochloride (500 mg)G0D334586ug/mg(an) ClindaMycin PalMitate HCl USP methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- 2-hexadecanoate-L-threo-α-D-galacto-octopyranoside,monohydrochloride Clindamycin Hydrochloride Palmitate Clindamycin 2-Palmitate HCl CLINDAMYCIN PALMITATE HCL Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl] carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside 2-Hexadecanoate Monohydrochloride hexadecanoic acid [6-[2-chloro-1-[[(1-methyl-4-propyl-2-pyrrolidinyl)-oxomethyl]amino]propyl]-4,5-dihydroxy-2-(methylthio)-3-oxanyl] ester Cleocin Pediatric Clindamycin Palmitate Hydrochloride (USP) Clindmycin palmitate hydrochloride USP/EP/BP Clindamycin palmitate hydrochloride USP/EP/BP Clindamycin Palmitate Hydrochloride (1137005) Clindamycin Impurity 85 25507-04-4 C34H63CIN2O6SHCL C18H33ClN2O5SHClC18H34Cl2 C34H64Cl2N2O6S C34H64Cl2N2O5S Inhibitors PHENYPASTEBAMIN