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ChemicalBook > Product Catalog >API >Antibiotics >Lincosamides Drugs >Clindamycin hydrochloride

Clindamycin hydrochloride

Clindamycin hydrochloride Structure
CAS No.
21462-39-5
Chemical Name:
Clindamycin hydrochloride
Synonyms
CLINDAMYCIN HCL;ClindaMycin-d3;CLEOCIN;Dalacin;7(S)-CHLORO-7-DEOXYLINCOMYCIN;Clindamycin hydrochloride, nonsterile;U-21251F;dalacina;Dalacin S;Clidamacin
CBNumber:
CB2398837
Molecular Formula:
C18H34Cl2N2O5S
Molecular Weight:
461.44
MOL File:
21462-39-5.mol
MSDS File:
SDS
Modify Date:
2024/7/26 16:29:23
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Clindamycin hydrochloride Properties

Melting point 141°C
storage temp. 2-8°C
solubility H2O: 50 mg/mL, clear, colorless
form Solid
color White to Off-White
BRN 4070786
Stability Hygroscopic
InChIKey AUODDLQVRAJAJM-XJQDNNTCSA-N
SMILES [C@@H]1([C@@H]([C@H](C)Cl)NC(=O)[C@@H]2C[C@@H](CCC)CN2C)[C@H](O)[C@H](O)[C@H]([C@@H](SC)O1)O.Cl |&1:0,1,2,8,10,17,19,21,22,r|
CAS DataBase Reference 21462-39-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317-H319-H362
Precautionary statements  P260-P263-P280-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  2
RTECS  GF2275000
F  10
HS Code  29419000

Clindamycin hydrochloride price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C5269 Clindamycin hydrochloride lincosamide antibiotic 21462-39-5 10MG ₹8789.9 2022-06-14 Buy
Sigma-Aldrich(India) C5269 Clindamycin hydrochloride lincosamide antibiotic 21462-39-5 50MG ₹21054.63 2022-06-14 Buy
Sigma-Aldrich(India) C5269 Clindamycin hydrochloride lincosamide antibiotic 21462-39-5 100MG ₹33514.2 2022-06-14 Buy
ottokemi C 6326 Clindamycin hydrochloride 21462-39-5 10mg ₹8001 2022-05-26 Buy
ottokemi C 6326 Clindamycin hydrochloride 21462-39-5 50mg ₹24039 2022-05-26 Buy
Product number Packaging Price Buy
C5269 10MG ₹8789.9 Buy
C5269 50MG ₹21054.63 Buy
C5269 100MG ₹33514.2 Buy
C 6326 10mg ₹8001 Buy
C 6326 50mg ₹24039 Buy

Clindamycin hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Clindamycin hydrochloride is a salt of clindamycin, a semi-synthetic lincosamide. The hydrochloride salt forms at the basic N-ethylproline moiety and is the preferred pharmaceutical formulation. Like other members of the lincosamide family, clindamycin is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Clindamycin hydrochloride acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Clindamycin hydrochloride has been extensively studied with over 8,000 literature citations.

General Description

Chemical structure: macrolide

Contact allergens

This lincosanide antibiotic is used in topical form for acne, or systemically has been responsible for exanthematous rashes and acute generalized exanthematous pustulosis.

Clinical Use

Clindamycin is recommended for the treatment of a widevariety of upper respiratory, skin, and tissue infections causedby susceptible bacteria. Its activity against streptococci,staphylococci, and pneumococci is indisputably high, and it isone of the most potent agents available against somenon–spore-forming anaerobic bacteria, the Bacteroides spp.in particular. An increasing number of reports of clindamycin-associated GI toxicity, which range in severity fromdiarrhea to an occasionally serious pseudomembranous colitis,have, however, caused some clinical experts to call for areappraisal of the role of this antibiotic in therapy.Clindamycin- (or lincomycin)-associated colitis may be particularlydangerous in elderly or debilitated patients and hascaused deaths in such individuals. The colitis, which is usuallyreversible when the drug is discontinued, is now believedto result from an overgrowth of a clindamycin-resistant strainof the anaerobic intestinal bacterium Clostridium difficile.229The intestinal lining is damaged by a glycoprotein endotoxinreleased by lysis of this organism.
The glycopeptide antibiotic vancomycin has been effectivein the treatment of clindamycin-induced pseudomembranouscolitis and in the control of the experimentally induced bacterial condition in animals. Clindamycin shouldbe reserved for staphylococcal tissue infections, such as cellulitisand osteomyelitis, in penicillin-allergic patients andfor severe anaerobic infections outside the central nervoussystem. Ordinarily, it should not be used to treat upper respiratorytract infections caused by bacteria sensitive to othersafer antibiotics or in prophylaxis.

Clindamycin hydrochloride Preparation Products And Raw materials

Raw materials

Ethanol Lincomycin Lincomycin hydrochloride monohydrate Lincomycin hydrochloride Acetonitrile

Preparation Products

Clindamycin hydrochloride Suppliers

Global( 664)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMXTREE STANDARDS +919872732255 Punjab, India 96 58 Inquiry
Vivimed Labs Ltd +914066086608 Telangana, India 61 58 Inquiry
Alfa Omega Pharma +91-8050045945 +91-9972665399 Maharashtra, India 126 58 Inquiry
aistrifarma +91-6374274350 +91-7708086868 Tamil Nadu, India 15 58 Inquiry
Synthink Research Chemicals 09158051123 Pune, India 398 58 Inquiry
Medvance Solution 91-9000487586 Hyderabad, India 137 58 Inquiry
Kebee Pharmachemie Pvt., Ltd. 91-22-28328669 Maharashtra, India 65 58 Inquiry
Eastern Chemicals (Mumbai) Pvt., Ltd. 91-22-67365900 Maharashtra, India 104 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Maas Pharma Chemicals +91-9958666224 Delhi, India 1607 58 Inquiry
Supplier Advantage
CHEMXTREE STANDARDS 58
Vivimed Labs Ltd 58
Alfa Omega Pharma 58
aistrifarma 58
Synthink Research Chemicals 58
Medvance Solution 58
Kebee Pharmachemie Pvt., Ltd. 58
Eastern Chemicals (Mumbai) Pvt., Ltd. 58
Pharma Affiliates 58
Maas Pharma Chemicals 58

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Clindamycin hydrochloride Spectrum

Clindamycin hydrochloride(21462-39-5)1HNMR

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Clindamycin IMP CLINDAMYCIN HYDROCHLORIDE, LINCOSAMI Clindamycin hydrochloride, nonsterileUSP, ≥ 860 μg/mg (2S-TRANS)-METHYL 7-CHLORO-6,7,8-TRIDEOXY-6[[(1-METHYL-4-PROPYL-2-PYRROLIDINYL)CARBONYL]AMINO]-1-THIO-L-THREO-ALPHA-D-GALACTO-OCTOPYRANOSIDE (7S)-7-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE 7(S)-CHLORO-7-DEOXYLINCOMYCIN HCL 7[S]-CHLORO-7-DEOXYLINCOMYCIN HYDROCHLORIDE CLEOCIN HYDROCHLORIDE CLINDAMYCIN HYDROCHLORIDE U-21251F (2S-trans)-Methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-alpha-D-galacto-octothiopyranoside monohydrochloride (7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin 7-chloro-7-deoxylincomycinhydrochloride clindimycinhydrochloride clindomycinhydrochloride dalacina Clidamacin Dalacin S Panancocin (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-Methyl-4-propyl-2- pyrrolidinyl]carbonyl]aMino]-1-thio- ClindaMycin hydrochloride Antipyrotic ClindaMycin HCL USP30 EP5 BP2007 Clindamycin Base & Phosphate Clindamycin hydrochloride,(7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin 7-Chloro-7-deoxylincoMycin hydrochloride, 7-ChlorolincoMycin hydrochloride (L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1)) Clindaymcin Hydrochloride BP98,USP25,EP97 L-threo-.alpha.-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride CLINDAMYCINHYDROCHLORIDE,CRYSTAL CLINDAMYCINHYDROCHLORIDE,USP Clindamycin hydrochloride, Antibiotic for Culture Media Use Only CLINDAMYCIN HC Lujiemycin monohydrochloride,(2s-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio CLINDAMYCIN HCI (7S)-7CHLORO-7-DEOXYLINCOMYCIN HCL (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2- pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside Hydrochloride Clindamycin hydrochloride Solution, 1000ppm Clindamycin Impurity 14(Clindamycin Phosphate EP Impurity E) (4R)-N-[(1S,2S)-2-chloro-1-[(3R,4R,6R)-3,4,5-trihydroxy-6-(methylthio)-2-oxanyl]propyl]-1-methyl-4-propyl-2-pyrrolidinecarboxamide hydrochloride Methyl-7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride Clindamycin hydrochloride CRS Clinimycin HCl Sobelin HCl indamycin HydrochL Clindamycin hydrochloride solution in Methanol, 1000ug/ml Clindamycin hydrochloride (USP, EP, oral grade) (2S,4R)-N-((1S,2S)-2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride Clindamycin hydrochloride salt lindamycin hydrochloride Clindamycin HydrochlorideQ: What is Clindamycin Hydrochloride Q: What is the CAS Number of Clindamycin Hydrochloride Q: What is the storage condition of Clindamycin Hydrochloride Q: What are the applications of Clindamycin Hydrochloride Clindamycin 13C D3 HydrochlorideQ: What is Clindamycin 13C D3 Hydrochloride Q: What is the CAS Number of Clindamycin 13C D3 Hydrochloride Q: What is the storage condition of Clindamycin 13C D3 Hydrochloride Q: What are the applications of Clindamycin 13C D3 Hydrochloride Clindamycin Hydrochloride (Cleocin) Clindamycin hydrochloride API CLEOCIN CLINDAMYCIN HCL Clindamycin hydrochloride, nonsterile Dalacin