ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >TGF-beta / Smad >TGF-beta / Smad inhibitors >ALK5 inhibitor II
ALK5 inhibitor II
- CAS No.
- 446859-33-2
- Chemical Name:
- ALK5 inhibitor II
- Synonyms
- RepSox;E-616452;CS-204;E616452;SJN 2511;E 616452;RepSox, >=98%;RepSox(E-616452;ALK5 INHIBITOR I;RepSox (SJN 2511)
- CBNumber:
- CB3806232
- Molecular Formula:
- C17H13N5
- Molecular Weight:
- 287.32
- MOL File:
- Mol file
- MSDS File:
- SDS
- Modify Date:
- 2024/11/17 16:00:36
| Melting point | 195 °C |
|---|---|
| Boiling point | 501.9±50.0 °C(Predicted) |
| Density | 1.296±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >20mg/mL |
| form | Yellow solid |
| pka | 10.05±0.50(Predicted) |
| color | Pale yellow |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| InChIKey | LBPKYPYHDKKRFS-UHFFFAOYSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 45 | |||||||||
| RIDADR | UN 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
ALK5 inhibitor II price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | R0158 | RepSox ≥98% (HPLC) | 446859-33-2 | 5MG | ₹14115.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | R0158 | RepSox ≥98% (HPLC) | 446859-33-2 | 25MG | ₹56874.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 616452 | TGF-β RI Kinase Inhibitor II - CAS 446859-33-2 - Calbiochem TGF-β RI Kinase Inhibitor II, CAS 446859-33-2, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of TGF-β R1 kinase (IC?? = 23 nM and | 446859-33-2 | 2MG | ₹23920.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 5.08158 | InSolution TGF-β RI Kinase Inhibitor II, RepSox - CAS 446859-33-2 - Calbiochem | 446859-33-2 | 5MG | ₹12940 | 2022-06-14 | Buy |
| TCI Chemicals (India) | R0224 | RepSox | 446859-33-2 | 5MG | ₹6600 | 2022-05-26 | Buy |
ALK5 inhibitor II Chemical Properties,Uses,Production
Uses
Alk 5 Inhibitor II is a selective ATP competitive inhibitor of transforming growth factor-β (TGFβ). A potential drug for the treatment of fibrosis and cancer.
Biochem/physiol Actions
RepSox Inhibits TGF-beta receptor signaling. Retroviral transduction of Sox2, Oct4, and Klf4 genes results in direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs).
ALK5 inhibitor II Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 185)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Intogen Biosciences | 08068441053Ext 900 | Hyderabad, India | 5 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | China | 29791 | 60 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | China | 9215 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32951 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29884 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39894 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Intogen Biosciences | 58 |
| Capot Chemical Co.,Ltd. | 60 |
| Hangzhou FandaChem Co.,Ltd. | 55 |
| ATK CHEMICAL COMPANY LIMITED | 60 |
| career henan chemical co | 58 |
| BOC Sciences | 58 |
| Chongqing Chemdad Co., Ltd | 58 |
446859-33-2(ALK5 inhibitor II)Related Search:
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ALK5 INHIBITOR I
2-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-1,5-NAPHTHYRIDINE
2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
SJN 2511
2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine
E 616452
E616452
1,5-Naphthyridine, 2-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-
RepSox 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine
RepSox, >=98%
RepSox(E-616452
TGF-BETA RI KINASE INHIBITOR II
TRANSFORMING GROWTH FACTOR-BETA TYPE I RECEPTOR KINASE INHIBITOR I
RepSox(ALK5 Inhibitor II)
TGF-β RI Kinase Inhibitor II
RepSox (SJN 2511)
ALK5 Inhibitor II
E-616452;SJN 2511;ALK5 INHIBITOR II;TGF-&BETA RI KINASE INHIBITOR II
TGF-β RI Kinase Inhibitor II - CAS 446859-33-2 - Calbiochem
InSolution TGF-β RI Kinase Inhibitor II, RepSox - CAS 446859-33-2 - Calbiochem
E-616452; SJN 2511; E616452; SJN2511; E 616452; SJN-2511
CS-204
E-616452
RepSox
2-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
446859-33-2
Selective inhibitor of the TGF-β type I receptor ALK5.
Smad
TGF-beta
Inhibitors