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ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >BOC-amino acid >1-Boc-4-methylpiperidine-4-carboxylic acid

1-Boc-4-methylpiperidine-4-carboxylic acid

1-Boc-4-methylpiperidine-4-carboxylic acid Structure
CAS No.
189321-63-9
Chemical Name:
1-Boc-4-methylpiperidine-4-carboxylic acid
Synonyms
1-Boc-4-MethyL;CHEMBRDG-BB 4002933;-4-piperidinecarboxyL;N-BOC-4-METHYL ISONIPECOTIC ACID;1-BOC-4-METHYL-ISONIPECOTIC ACID;4-METHYL-4-CARBOXY-1-N-BOC-PIPERIDINE;N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID;1-Boc-4-methyl-4-piperidinecarboxylic Acid;1-BOC-4-METHYL-PIPERIDINE-4-CARBOXYLIC ACID;N-Boc-4-Methyl-piperidine-4-carboxylic acid/
CBNumber:
CB4192851
Molecular Formula:
C12H21NO4
Molecular Weight:
243.3
MOL File:
189321-63-9.mol
MSDS File:
SDS
Modify Date:
2024/1/10 9:07:12
Request For Quotation

1-Boc-4-methylpiperidine-4-carboxylic acid Properties

Boiling point 354.3±35.0 °C(Predicted)
Density 1.129±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 4.69±0.20(Predicted)
InChI InChI=1S/C12H21NO4/c1-11(2,3)17-10(16)13-7-5-12(4,6-8-13)9(14)15/h5-8H2,1-4H3,(H,14,15)
InChIKey OKBNEDPOUYRYNP-UHFFFAOYSA-N
SMILES N1(C(OC(C)(C)C)=O)CCC(C)(C(O)=O)CC1
CAS DataBase Reference 189321-63-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
RIDADR  UN2811
HazardClass  IRRITANT
HS Code  2933399990

1-Boc-4-methylpiperidine-4-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

White to Light yellow powder to crystal

Synthesis

A mixture of Ethyl N-Boc-4-methylpiperidine-4-carboxylate (4.1 g, 15.1mmol) and lithium hydroxide (2.17g, 90.6mmol) in methanol (3OmL)ZH2O (2OmL) was stirred at a temperature of about 25 ℃ for 16h. After evaporation to dryness, the residue was partitioned between DCM and brine. The organic layer was separated, dried (MgSO4), filtered, and concentrated under reduced pressure to provide 3.38g of 1-Boc-4-methylpiperidine-4-carboxylic acid as a white solid (yield 92.0 percent).

1-Boc-4-methylpiperidine-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Ethanol Di-tert-butyl dicarbonate Diisopropylamine Lithium hydroxide monohydrate Tetrahydrofuran
Ammonium chloride Ethyl 4-piperidinecarboxylate Ethyl acetate Hydrochloric acid Dichloromethane
Methanol PETROLEUM ETHER Iodomethane n-Butyllithium
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Preparation Products

1-Boc-4-methylpiperidine-4-carboxylic acid Suppliers

Global( 150)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29900 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd +8613580539051 CHINA 21149 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26114 58 Inquiry
Supplier Advantage
A.J Chemicals 58
LEAPCHEM CO., LTD. 58
Capot Chemical Co.,Ltd. 60
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Fuxin Pharmaceutical 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 58
Dideu Industries Group Limited 58

1-Boc-4-methylpiperidine-4-carboxylic acid Spectrum

1-Boc-4-methylpiperidine-4-carboxylic acid(189321-63-9)1HNMR

189321-63-9(1-Boc-4-methylpiperidine-4-carboxylic acid)Related Search:

o-Toluic acid p-Toluic acid Triacetonediamine 2,2,6,6-Tetramethyl-4-piperidinol tert-Butyl carbazate
1,2,2,6,6-Pentamethyl-4-piperidinol Isonipecotic acid BOC-4-PHENYLPIPERIDINE-4-CARBOXYLIC ACID 1-BOC-4-ETHYL-4-PIPERIDINECARBOXYLIC ACID Ethyl N-Boc-4-methylpiperidine-4-carboxylate
N-Boc-3-Methylnipecotic acid ethyl ester 1-N-Boc-3-Methylpiperidine-3-carboxylic acid BOC-4-CYCLOHEXYL-PIPERIDINE-4-CARBOXYLIC ACID N-BOC-4-(P-FLUOROPHENYL)-4-PIPERIDINECARBOXYLIC ACID 1,4-Piperidinedicarboxylic acid, 4-(2-propen-1-yl)-, 1-(1,1-dimethylethyl) ester
METHYL 4-AMINOMETHYL-1-BOC-PIPERIDINE-4-CARBOXYLATE N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC ACID N-BOC-4-(P-CHLOROPHENYL)-4-PIPERIDINE CARBOXYLIC ACID
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N-BOC-4-METHYL ISONIPECOTIC ACID N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACID N-BOC-4-METHYL-4-PIPERIDINECARBOXYLIC ACID CHEMBRDG-BB 4002933 4-METHYL-4-CARBOXY-1-N-BOC-PIPERIDINE 4-METHYL-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-TERT-BUTYL ESTER 1-BOC-4-METHYL-PIPERIDINE-4-CARBOXYLIC ACID 1-Boc-4-methyl-4-piperidinecarboxylic Acid 1-(tert-Butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid N-BOC-4-METHYL-4-METHYLPIPERIDINECARBOXYLIC ACIDN-BOC-4-METHYL ISONIPECOTIC ACID 1-N-Boc-4-methyl-piperidine-4-carboxylic acid 1-BOC-4-METHYL-ISONIPECOTIC ACID 1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) ester 1,4-piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethy 1-Boc-4-methyl-piperidine-4-carboxylic acid ,98% 1-(tert-butoxycarbonyl)-4-methylpiperidine-4-carboxylic acid(SALTDATA: FREE) N-Boc-4-Methyl-piperidine-4-carboxylic acid/ 1-tert-butoxycarbonyl-4-methyl-isonipecotic acid 4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylic acid 1-(tert-butoxy-oxomethyl)-4-methyl-4-piperidinecarboxylic acid 1-Boc-4-MethyL -4-piperidinecarboxyL 4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-4-carboxylicaci 1-Boc-4-methylpiperidine-4-carboxylic acid USP/EP/BP 1,4-Piperidinedicarboxylic acid, 4-methyl-, 1-(1,1-dimethylethyl) ester (9CI, ACI) 4-methyl-1,4-Piperidinedicarboxylic acid 1-(1,1-dimethylethyl) ester (9CI ACI) 189321-63-9 API intermediates Amino Acids and Derivatives Heterocycles Pyridines