ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >protein tyrosine kinase >AG 1478 HYDROCHLORIDE
AG 1478 HYDROCHLORIDE
- CAS No.
- 153436-53-4
- Chemical Name:
- AG 1478 HYDROCHLORIDE
- Synonyms
- -1478);AG-1478;AG1478HCl;NSC 693255;AG-1478, >98%;AG-1478 AG1478;AG-1478 (NSC-693255);-1478 (Tyrphostin Ag;AG 1478 HYDROCHLORIDE;AG-1478 (Tyrphostin AG-1478)
- CBNumber:
- CB4728982
- Molecular Formula:
- C16H14ClN3O2
- Molecular Weight:
- 315.75
- MOL File:
- 153436-53-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:01:57
| Melting point | 247 °C(dec.) |
|---|---|
| Boiling point | 458.5±45.0 °C(Predicted) |
| Density | 1.337 |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | insoluble in H2O; ≥15.8 mg/mL in DMSO; ≥2.38 mg/mL in EtOH with gentle warming |
| pka | 5.54±0.30(Predicted) |
| form | White to light yellow solid. |
| color | Light orange to Yellow to Green |
| λmax | 332nm(lit.) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H332-H335 | |||||||||
| Precautionary statements | P280-P305+P351+P338-P310 | |||||||||
| RTECS | VA0953000 | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
AG 1478 HYDROCHLORIDE Chemical Properties,Uses,Production
Uses
A highly potent and specific EGFR tyrosine kinase inhibitor with an IC50 of 3 nM.
Biological Activity
Potent and selective inhibitor of epidermal growth factor receptor kinase (IC 50 values 3 nM for EGFR and > 100 μ M for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC 50 = 1 μ M).
AG 1478 HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 146)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25655 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
153436-53-4(AG 1478 HYDROCHLORIDE)Related Search:
chevron_left
1of4
chevron_right
N-(3-CHLOROPHENYL)-6,7-DIMETHOXY-4-QUINAZOLINANINE HYDROCHLORIDE
4-(3-CHLOROANILINO)-6,7-DIMETHOXYQUINAZOLINE HCL
4-(3-CHLOROANILINO)-6,7-DIMETHOXYQUINAZOLINE HYDROCHLORIDE
AG-1478
AG 1478 HYDROCHLORIDE
Tyrphostin AG 1478, free base >99%
NSC 693255
(3-Chlorophenyl)(6,7-dimethoxyquinazolin-4-yl)amine
AG1478HCl
AG-1478 (Tyrphostin AG-1478)
AG-1478 (NSC-693255)
AG-1478, 97.5%, a selective EGFR inhibitor
AG1478; TYRPHOSTIN AG1478; AG 1478; NSC 693255
AG1478; TYRPHOSTIN AG1478; AG 1478
AG-1478, >98%
-1478 (Tyrphostin Ag
-1478)
AG 1478 HYDROCHLORIDE USP/EP/BP
AG-1478 AG1478
AG-1478 hydrochloride/Tyrphostin AG 1478
153436-53-4
C16H14ClN3O2HCl
Inhibitors
API
Inhibitor