2-Amino-5-nitrophenol
- CAS No.
- 121-88-0
- Chemical Name:
- 2-Amino-5-nitrophenol
- Synonyms
- 5-NITRO-2-AMINOPHENOL;2-HYDROXY-4-NITROANILINE;NSC 7087;CI 76535;rodolyba;ncic55970;Sulpho OAVS;ursolyellowbrowna;2-AMINO-5-NITROPENOL;2-AMINO-5-NIRTO PHENO
- CBNumber:
- CB5436138
- Molecular Formula:
- C6H6N2O3
- Molecular Weight:
- 154.12
- MOL File:
- 121-88-0.mol
- Modify Date:
- 2023/5/15 10:43:13
| Melting point | 198-202 °C (dec.) (lit.) |
|---|---|
| Boiling point | 322.46°C (rough estimate) |
| Density | 1.3617 (estimate) |
| refractive index | 1.6890 (rough estimate) |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 8.08±0.19(Predicted) |
| color | Rust brown to brown |
| Water Solubility | insoluble |
| BRN | 972974 |
| CAS DataBase Reference | 121-88-0(CAS DataBase Reference) |
| IARC | 3 (Vol. 57) 1993 |
| EPA Substance Registry System | 2-Amino-5-nitrophenol (121-88-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-68-20/21/22 | |||||||||
| Safety Statements | 26-36/37-45-36/37/39-36 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | SJ6302500 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29222900 | |||||||||
| Toxicity | LD50 oral in rat: > 4gm/kg | |||||||||
| NFPA 704 |
|
2-Amino-5-nitrophenol price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 303585 | 2-Amino-5-nitrophenol | 121-88-0 | 25G | ₹4351.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 303585 | 2-Amino-5-nitrophenol | 121-88-0 | 100G | ₹8454.33 | 2022-06-14 | Buy |
| ALFA India | ALF-B20870-22 | 2-Amino-5-nitrophenol, 95% | 121-88-0 | 100g | ₹6059 | 2022-05-26 | Buy |
| ALFA India | ALF-B20870-14 | 2-Amino-5-nitrophenol, 95% | 121-88-0 | 25g | ₹2400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N0113 | 2-Amino-5-nitrophenol min. 98.0 % | 121-88-0 | 25G | ₹2600 | 2022-05-26 | Buy |
2-Amino-5-nitrophenol Chemical Properties,Uses,Production
Chemical Properties
Brown to rust Crystalline powder
Uses
2-Amino-5-nitrophenol is used in hair dyes and as an intermediate in preparing azo dyes.
General Description
Brown amorphous granules or powder. Melting point 198-202°C.
Air & Water Reactions
Is slowly oxidized by air at room temperature. Insoluble in water.
Reactivity Profile
2-Amino-5-nitrophenol is a reducing agent. Incompatible with strong oxidizing agents. Reacts slowly with oxygen in the air at room temperature. Stable at temperatures up to 140°F for two weeks when kept in the dark and under nitrogen. Stable under nitrogen for up to 24 weeks 77°F. Incompatible with strong bases . Incompatible with acid chlorides and acid anhydrides.
Fire Hazard
Flash point data for 2-Amino-5-nitrophenol are not available. 2-Amino-5-nitrophenol is probably combustible.
Carcinogenicity
The potential carcinogenicity of 2-amino-5-nitrophenol was tested by NTP by oral administration (gavage) in corn oil to F344/N rats (100 and 200 mg/kg) and B6C3F1 mice (400 and 800 mg/kg) for 2 years. There was some evidence of carcinogenic activity in low-dose male rats, as indicated by increased incidence of acinar cell adenomas of the pancreas. No evidence of carcinogenic activity was found among female rats and the low-dose groups of male and female mice. The poor survival rates in the high-dose male rats and high-dose male and female mice reduced the sensitivity for detecting potential carcinogenic response.
Purification Methods
Crystallise the phenol from water. [Beilstein 13 IV 803.]
2-Amino-5-nitrophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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