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Boc-D-Ser(Bzl)-OH

CAS No.: 47173-80-8

Chemical Name:: Boc-D-Ser(Bzl)-OH

Synonyms: O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE;BOC-SER(BZL)-OH;BOC-SER(BZL);BOC-D-SER(BZL);BOC-O-BENZYL-L-SERINE;(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid;(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;BOC-L-SER(BZL);(2R)-3-(benzylox;BOC-D-SER(BZL)-OH

CBNumber:: CB5438415

Molecular Formula:: C15H21NO5

Molecular Weight:: 295.33

MOL File:: 47173-80-8.mol

MSDS File:: SDS

Modify Date:: 2024/5/16 10:38:43

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Boc-D-Ser(Bzl)-OH Properties

Melting point	58-60 °C(lit.)
alpha	-19 º (c=2 80% alcohol)
Boiling point	437.02°C (rough estimate)
Density	1.1454 (rough estimate)
refractive index	-20 ° (C=2, 80% EtOH)
storage temp.	Sealed in dry,Room Temperature
solubility	almost transparency in Methanol
pka	3.53±0.10(Predicted)
form	Powder
color	White
BRN	2665080
InChI	InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1
InChIKey	DMBKPDOAQVGTST-GFCCVEGCSA-N
SMILES	C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference	47173-80-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

Risk Statements

20/21/22-36/37/38

Safety Statements

24/25-36-26

WGK Germany

HS Code

2924 29 70

HazardClass

IRRITANT

NFPA 704

	1
0		0

Boc-D-Ser(Bzl)-OH price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	8.53111	Boc-D-Ser(Bzl)-OH Novabiochem?	47173-80-8	25G	₹13090	2022-06-14	Buy
Sigma-Aldrich(India)	15078	Boc-D-Ser(Bzl)-OH ≥98.0% (HPLC)	47173-80-8	5G	₹20491.73	2022-06-14	Buy
TCI Chemicals (India)	B1863	O-Benzyl-N-(tert-butoxycarbonyl)-D-serine	47173-80-8	1G	₹3800	2022-05-26	Buy
TCI Chemicals (India)	B1863	O-Benzyl-N-(tert-butoxycarbonyl)-D-serine	47173-80-8	5G	₹16200	2022-05-26	Buy

Product number	Packaging	Price	Buy
8.53111	25G	₹13090	Buy
15078	5G	₹20491.73	Buy
B1863	1G	₹3800	Buy
B1863	5G	₹16200	Buy

Boc-D-Ser(Bzl)-OH Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Biological Activity

Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.

Synthesis

N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.

Boc-D-Ser(Bzl)-OH Preparation Products And Raw materials

Raw materials

O-Benzyl-D-serine Di-tert-butyl dicarbonate Benzyl bromide

Preparation Products

MK-677 Carbamic acid, N-[(1R)-1-formyl-2-(phenylmethoxy)ethyl]-, 1,1-dimethylethyl ester Boc-N-Me-D-Ser(Bzl)-OH

Boc-D-Ser(Bzl)-OH Suppliers

Global( 269)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
TEADUS PHARMA PRIVATE LIMITED	+91-9740077663 +91-9740077663	Telangana, India	242	58	Inquiry
SV CHEM INTERMEDITES PRIVATE LIMITED	+91-9940629423 +91-9940629423	Tamil Nadu, India	202	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
Maas Pharma Chemicals	+91-9958666224	Delhi, India	1607	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
Chempure	08047626574	Mumbai, India	144	58	Inquiry
Santo Righello Pvt. Ltd	91-9885571757	Hyderabad, India	919	58	Inquiry
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-028-64841719 +8617390183901	China	1106	58	Inquiry

Supplier	Advantage
TEADUS PHARMA PRIVATE LIMITED	58
SV CHEM INTERMEDITES PRIVATE LIMITED	58
JSK Chemicals	58
Maas Pharma Chemicals	58
A.J Chemicals	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58
Chempure	58
Santo Righello Pvt. Ltd	58
Sichuan HongRi Pharma-Tech Co.,Ltd	58

Boc-D-Ser(Bzl)-OH Spectrum

N-Boc-O-Benzyl-D-serine(47173-80-8)MS N-Boc-O-Benzyl-D-serine(47173-80-8)¹HNMR N-Boc-O-Benzyl-D-serine(47173-80-8)¹³CNMR N-Boc-O-Benzyl-D-serine(47173-80-8)IR1 N-Boc-O-Benzyl-D-serine(47173-80-8)IR2

47173-80-8(Boc-D-Ser(Bzl)-OH)Related Search:

Benzyl chloride D-Serine Benzyl benzoate L-Homoserine tert-Butanol

Boc-Ser(tBu)-OH N-Carbobenzyloxyglycine Benzyl bromide DL-Serine Benzyltriethylammonium chloride

Benzyl alcohol L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE Boc-Aib-OH D-Cycloserine Benzyltrimethylammonium chloride

Boc-O-benzyl-L-serine, N-(tert-Butoxycarbonyl)-O-benzyl-L-serine,N-BOC-O-Benzyl-L-serine,N-T-BOC-O-BENZYL-L-SERINE CRYSTALLINE BOC-GLY-LEU-OH Boc-His(Trt)-OH

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(2R)-2-(tert-butoxycarbonylamino)-3-(phenylmethoxy)propanoic acid (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethoxy)propanoic acid (2R)-2-[(tert-butoxy-oxomethyl)amino]-3-(phenylmethoxy)propanoic acid (2R)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propionic acid L-Serine, N-((1,1-dimethylethoxy)carbonyl)-O-(phenylmethyl)- Boc-D-Ser(Bzl)-OH, >=98% BOC-D-SERINE(BZL)-OH BOC-D-SER(BZL)-OH BOC-SERINE(BZL)-OH BOC-(S)-2-AMINO-3-BENZYLOXYPROPIONIC ACID BOC-O-BENZYL-D-SERINE BOC-(R)-2-AMINO-3-BENZYLOXYPROPIONIC ACID BOC-L-SER(BZL)-OH BOC-L-SERINE (BZL) BOC-L-SER(BZL) O-Benzyl-N-(tert-butoxycarbonyl)-D-serine Boc-O-benzyl-D-serine≥ 99.5% (HPLC) NALPHA-tert-Butoxycarbonyl-O-benzyl-D-serine N-BOC-O-Benzyl-D-serine,98% N-t-BOC-O-Benzyl-D-serine N-Boc-O-Benzyl-D-ser Boc-D-Ser(Bzl)-OH Boc-O-benzyl-D-Serine N-Boc-O-benzyl-D-serine Boc-D-Ser(Bzl)-OH T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE T-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE TBOC-L-SERINE (BZL) N-ALPHA-T-BOC-O-BENZYL-L-SERINE N-ALPHA-T-BOC-O-BENZYL-D-SERINE N-ALPHA-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE N-ALPHA-TERT-BOC-O-BENZYL-L-SERINE N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE N-BOC-O-BENZYL-D-SERINE Boc-DL-Ser(Bzl)-OH N-TERT-BUTOXYCARBONYL-O-BENZYL-D-SERINE N-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE (Tert-Butoxy)Carbonyl D-Ser(Bzl)-OH (2R)-3-(benzylox O-Benzyl-N-Boc-D-serine O-Benzyl-N-(tert-butoxycarbonyl)-D-serine > D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- BOC-SER(BZL)-OH BOC-SER(BZL) BOC-O-BENZYL-L-SERINE (R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE BOC-D-SER(BZL) (2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid N-[(1,1-Dimethylethoxy)carbonyl]-O-(phenylmethyl)-D-serine (s)-(+)-3-Benzyloxy-2-(Boc-amino)-1-propanol BOC-D-Ser(OBZL)-OH 47173-80-8 47473-80-8 47173-80-6 C15H20NO5 Specialty Synthesis Peptide Synthesis