ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Aromatic acids >4-Chlorobenzoic acid
4-Chlorobenzoic acid
- CAS No.
- 74-11-3
- Chemical Name:
- 4-Chlorobenzoic acid
- Synonyms
- 74-11-3;PCBA;4-CHLOROBENZOATE;P-CHLOROBENZOIC ACID;Acemetacin impurity A CRS;4-chlorobenzoic;Indomethacin Related Compound B;Mycosid;NSC 8444;NSC 32738
- CBNumber:
- CB5482423
- Molecular Formula:
- C7H5ClO2
- Molecular Weight:
- 156.57
- MOL File:
- 74-11-3.mol
- Modify Date:
- 2024/4/15 18:41:30
| Melting point | 238-241 °C(lit.) |
|---|---|
| Boiling point | 274-276 °C |
| Density | 1.540 |
| refractive index | 1.5812 (estimate) |
| Flash point | 238 °C |
| storage temp. | room temp |
| solubility | methanol: soluble1%, clear, colorless to faintly yellow |
| form | Crystalline Powder |
| pka | 3.98(at 25℃) |
| color | White to yellow |
| PH | 4.3 (0.08g/l, H2O, 20℃) |
| Water Solubility | soluble in hot water |
| λmax | 284nm(EtOH)(lit.) |
| Merck | 14,2125 |
| BRN | 907196 |
| Stability | Stable. Combustible. Incompatible with bases, strong oxidizing agents. |
| InChIKey | XRHGYUZYPHTUJZ-UHFFFAOYSA-N |
| LogP | 2.650 |
| CAS DataBase Reference | 74-11-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzoic acid, 4-chloro-(74-11-3) |
| EPA Substance Registry System | p-Chlorobenzoic acid (74-11-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | DG4976010 | |||||||||
| Autoignition Temperature | 545 °C | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29163900 | |||||||||
| Toxicity | LD50 orally in Rabbit: 1170 mg/kg | |||||||||
| NFPA 704 |
|
4-Chlorobenzoic acid price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 135585 | 4-Chlorobenzoic acid 99% | 74-11-3 | 50G | ₹1916.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2581 | Indomethacin Related Compound B Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 50?mg | 74-11-3 | 50MG | ₹45529.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 135585 | 4-Chlorobenzoic acid 99% | 74-11-3 | 250G | ₹3215.03 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C0134 | 4-Chlorobenzoic Acid min. 99.0 % | 74-11-3 | 25G | ₹2000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C0134 | 4-Chlorobenzoic Acid min. 99.0 % | 74-11-3 | 100G | ₹3200 | 2022-05-26 | Buy |
4-Chlorobenzoic acid Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder. Soluble in methanol, anhydrous ethanol and ether, very slightly soluble in water, toluene and 95% ethanol.
Uses
4-Chlorobenzoic acid can be used:
As a ligand to synthesize luminescent lanthanide complexes for bio-labeling or fiber communication applications.
To prepare organotin(IV) chlorobenzoates exhibiting anticorrosion properties.
As a ligand to synthesize di-n-butyl(4-chlorobenzoxy)(4-chlorobenzohydroxamato)tin(IV).
Definition
ChEBI: 4-chlorobenzoic acid is a monochlorobenzoic acid carrying a chloro substituent at position 4. It has a role as a bacterial xenobiotic metabolite. It derives from a benzoic acid. It is a conjugate acid of a 4-chlorobenzoate.
General Description
Triclinic crystals or light fluffy white powder.
4-Chlorobenzoic acid is a degradation product of indomethacin. It is degraded by Acinetobacter sp. strain ST-1 and causes its dehalogenation to yield 4-hydroxybenzoic acid under both aerobic and anaerobic conditions.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
4-Chlorobenzoic acid is incompatible with strong oxidizing agents and strong bases.
Fire Hazard
Flash point data for 4-Chlorobenzoic acid are not available; however, 4-Chlorobenzoic acid is probably combustible.
Purification Methods
Purify it as for m-chlorobenzoic acid. It has also been crystallised from hot water, and from EtOH. [Beilstein 9 IV 973.]
4-Chlorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Moclobemide
4-Chloro-3,5-dinitrobenzoic acid
2-Amino-5-nitrobenzophenone
3-Amino-4-methoxybenzanilide
4-Chloro-3-nitrobenzoic acid
4-Chlorobenzoyl chloride
Bumetanide
Dimethyl terephthalate
Mebendazole
2-chloro-4-(4-chlorophenyl)-6-phenyl-1,3,5-triazine
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Global( 650)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| sdichem | +91-9724342202 +91-9724342202 | Gujarat, India | 13 | 58 | Inquiry |
| OPULENT PHARMA | +91-9106692785 +91-9106692785 | Gujarat, India | 479 | 58 | Inquiry |
| VGS SYNTHESIS PRIVATE LIMITED | +91-9866975588 +91-9866975588 | Hyderabad, India | 1818 | 58 | Inquiry |
| Technichem Organics Pvt ltd | +91-9429893561 +91-9429893561 | Ahmedabad, India | 49 | 58 | Inquiry |
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| Orgamine Chemicals(I) Pvt Ltd | +91-9820080281 +91-9820080281 | Maharashtra, India | 451 | 58 | Inquiry |
| Supharma Chem | +91-9428180908 +91-9428180908 | Gujarat, India | 10 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| sdichem | 58 |
| OPULENT PHARMA | 58 |
| VGS SYNTHESIS PRIVATE LIMITED | 58 |
| Technichem Organics Pvt ltd | 58 |
| JSK Chemicals | 58 |
| Chemcrux Enterprises Ltd | 58 |
| Orgamine Chemicals(I) Pvt Ltd | 58 |
| Supharma Chem | 58 |
| Pharmaffiliates Analytics and Synthetics P. Ltd | 58 |
74-11-3(4-Chlorobenzoic acid)Related Search:
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AKOS 92635
AKOS BBS-00003713
RARECHEM AL BO 0054
4-Chlorbenzoesαure
4-chloro-benzoicaci
Acido p-clorobenzoico
acidop-clorobenzoico
Benzoic acid, p-chloro-
benzoicacid,4-chloro-
p-CHLOROBENZOIC ACID pure
4-Chlorobenzoic acid,99%
p-Chorobenzoic acid
4-Chlorobenzoic acid, 99% 250GR
4-Chlorobenzoic acid, 99% 25GR
Mycosid
NSC 143358
NSC 32738
NSC 8444
4-CHLOROBENZOIC ACID FOR SYNTHESIS
4-chlorobenzoic aicd
4-Chlorobenzoic acid Vetec(TM) reagent grade, 98%
Of chlorobenzoic acid
4-Chlorobenzoi
'LGC' (4004)
LABOTEST-BB LT00776185
CHLORODRACYLIC ACID
4-CHLOROBENZOIC ACID
para-chlorobenzoicacid
p-Carboxychlorobenzene
p-Chlorbenzoic acid
p-chlorbenzoicacid
p-chlorobenzoic
p-chloro-benzoicaci
4-CHLOROBENZOIC ACID, 1000MG, NEAT
ChlorocholineChloride50%AqueousSolution
4-Chlorobenzoic acid, 98+%
Chlorodracyclic acid
p-CHLOROBENZOIC ACID extrapure AR
Indometacin EP Impurity A
Indomethacin EP Impurity A
Acemetacin Impurity 1（Acemetacin EP Impurity A）
Bezafibrate Impurity 2（Bezafibrate EP Impurity B）
Indomethacin USP RC B
4-Chlorobenzoic Acid (Indomethacin Impurity)
Bezafibrate EP Impurity B
Indomethacin Impurity 15
Acemetacin EP Impurity A (Indomethacin EP Impurity A/ Indomethacin Related Compound B/ Bezafibrate EP Impurity B)
Bezafibrate EP Impurity B (Acemetacin EP Impurity A/ Indomethacin EP Impurity A/ Indomethacin Related Compound B)
Indomethacin EP Impurity A/ Indomethacin Related Compound B (Acemetacin EP Impurity A/ Bezafibrate EP Impurity B)
Indometacin Impurit Ⅱ:4-Chlorobenzoic acid
p-Chlorobenzoic Acid extrapure AR, 99.7%
Indomethacin Related Compound B (4-chlorobenzoic acid) (1112423)
PCBA
P-CHLOROBENZOIC ACID
4-chlorobenzoic
74-11-3
4-CHLOROBENZOATE
Indomethacin Related Compound B