Alprazolam
- CAS No.
- 28981-97-7
- Chemical Name:
- Alprazolam
- Synonyms
- Xanax;Zolam;Trankimazin;8-Chloro-1-methyl-6-phenyl-4H-2,3,5,10b-tetraazabenzo[e]azulene;8-CHLORO-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPINE;d65mt;Tafil;TUS-1;Xanor;C06817
- CBNumber:
- CB6141398
- Molecular Formula:
- C17H13ClN4
- Molecular Weight:
- 308.76
- MOL File:
- 28981-97-7.mol
- Modify Date:
- 2023/6/8 9:03:07
| Melting point | 228-228.50C |
|---|---|
| Boiling point | 463.51°C (rough estimate) |
| Density | 1.2000 (rough estimate) |
| refractive index | 1.6110 (estimate) |
| Flash point | 11 °C |
| storage temp. | 2-8°C |
| solubility | H2O: insoluble |
| pka | 2.37±0.40(Predicted) |
| Water Solubility | 70mg/L(ambient temperature) |
| BCS Class | 1 |
| CAS DataBase Reference | 28981-97-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Alprazolam(28981-97-7) |
| EPA Substance Registry System | Alprazolam (28981-97-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| Hazard Codes | Xn,T,F | |||||||||
| Risk Statements | 22-39/23/24/25-23/24/25-11 | |||||||||
| Safety Statements | 36-45-36/37-16-7 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XZ5473000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2933910000 | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 1020, >2000 orally; 540, 610 i.p. (Nakajima) | |||||||||
| DEA Controlled Substances | CSCN: 2882 CAS SCH: Ⅳ NARC: N |
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| NFPA 704 |
|
Alprazolam Chemical Properties,Uses,Production
Description
Alprazolam (Item No. 14255) is an analytical reference material categorized as a benzodiazepine. Alprazolam is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.
Chemical Properties
White Crystalline Solid
Uses
Controlled substance (depressant). Anxiolytic
Definition
ChEBI: A member of the class of triazolobenzodiazepines that is 4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine carrying methyl, phenyl and chloro substituents at positions 1, 6 and 8 respectively. Alprazolam is only found in individu ls that have taken this drug.
General Description
Alprazolam, 8-chloro-1-methyl-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine (Xanax), israpidly absorbed from the GI tract. Protein binding is lower(～70%) than with most benzodiazepines because of itslower lipophilicity.α-Hydroxylation of the methyl group tothe methyl alcohol (a reaction analogous to benzylic hydroxylation)followed by conjugation is rapid; consequently,the duration of action is short. The drug is a highlypotent anxiolytic on a milligram basis.
Alprazolam Preparation Products And Raw materials
Raw materials
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