ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >Beta Amyloid Inhibitors >EUK 134
EUK 134
- CAS No.
- 81065-76-1
- Chemical Name:
- EUK 134
- Synonyms
- EUK 134;ETHYLBISIMINOMETHYLGUAIACOL MANGANESE CHLORIDE;SALEN-MN;Salen-Mn-Cl;SALEN-MN/EUK-134;SALEN-MN USP/EP/BP;EUK 134, SOD/catalase mimetic;Manganese (salen-3,3'-diMethoxy) chloride;Ethylbis aminomethyl Guaiacol manganese chloride;ethylbisiminomethylguaiacol manganese chloride (EUK134)
- CBNumber:
- CB6291079
- Molecular Formula:
- C18H18ClMnN2O4
- Molecular Weight:
- 416.74
- MOL File:
- 81065-76-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/26 17:21:34
| storage temp. | -20°C |
|---|---|
| solubility | H2O: soluble2mg/mL, clear (warmed) |
| form | powder |
| color | faint to very dark brown |
| InChI | InChI=1S/C18H20N2O4.ClH.Mn/c1-23-15-7-3-5-13(17(15)21)11-19-9-10-20-12-14-6-4-8-16(24-2)18(14)22;;/h3-8,11-12,21-22H,9-10H2,1-2H3;1H;/q;;+3/p-3/b19-11+,20-12+;; |
| InChIKey | YUZJJFWCXJDFOQ-GAMUHHASSA-K |
| SMILES | [Cl-][Mn+3]123[O-]C4C(=CC=CC=4C=N1CCN2=CC1=CC=CC(OC)=C1[O-]3)OC |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| WGK Germany | 3 |
EUK 134 price More Price(2)
EUK 134 Chemical Properties,Uses,Production
Uses
EUK-134 has been used as an antioxidant.
benefits
EUK-134 has been used as an antioxidant. An antioxidant serum that protects the skin from pollution and other external aggressors. In addition, it helps to reduce the appearance of redness and UV damage such as pigmentation and dark spots.
Biochem/physiol Actions
EUK-134 is a manganese-salen derivative that exhibit potent antioxidant activities. EUK-134 is a superoxide dismutase (SOD) that inhibits amyloid fibril formation, including islet amyloid polypeptide (IAPP), β-amyloid and lysozyme amyloid aggregation. It appears that EUK-134 disrupts the pre-formed amyloid fibrils. EUK-134 increases the viability of the SK-N-MC cells exposed to preformed IAPP fibrils.
EUK 134 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 154)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ZhenYiBio Technology Inc | +8615309206328 | China | 298 | 58 | Inquiry |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +86-18580541567 +86-17782035140 | China | 301 | 58 | Inquiry |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20296 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | China | 952 | 58 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10312 | 58 | Inquiry |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | China | 7513 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
81065-76-1(EUK 134 )Related Search:
CHLORO[[2,2'-[1,2-ETHANEDIYLBIS[(NITRILO-KAPPAN)METHYLIDYNE]]BIS[6-METHOXYPHENOLATO-KAPPAO]]]-MANGANESE
SALEN-MN
Chloro[[2,2'-[1,2-ethanediylbis(nitrilomethylidyne)]bis[6-methoxyphenolato]](2-)-N2,N2',O1,O1']manganese
SALEN-MN/EUK-134
Manganese (salen-3,3'-diMethoxy) chloride
chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]]]-manganese
(SP-5-13)-Chloro[[2,2′-[1,2-ethanediylbis[(nitrilo-?N)methylidyne]]bis[6-methoxyphenolato-KO]](2-)]-manganese
2,2′-[1,2-Ethanediylbis(nitrilomethylidyne)]bis[6-methoxy-phenol manganese complex
chloro(bis(3,3′di-methoxysalicylidene)ethylenediamine)manganese
EUK 134, SOD/catalase mimetic, Ethylbisiminomethylguaiacol manganese chloride
EUK 134, SOD/catalase mimetic
manganese(2+),2-methoxy-6-[2-[(3-methoxy-2-oxidophenyl)methylideneamino]ethyliminomethyl]phenolate,chloride
SALEN-MN USP/EP/BP
Manganese,chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-kN)methylidyne]]bis[6-methoxyphenolato-kO]](2-)]-,(SP-5-13)-
Salen-Mn-Cl
manganous 2-methoxy-6-[(E)-2-[(E)-(3-methoxy-2-oxido-phenyl)...
EUK 134
ETHYLBISIMINOMETHYLGUAIACOL MANGANESE CHLORIDE
(SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]manganese
ethylbisiminomethylguaiacol manganese chloride (EUK134)
Manganous 2-methoxy-6-[(E)-2-[(E)-(3-methoxy-2-oxido-phenyl)methyleneamino]ethyliminomethyl]phenolate chloride
Ethylbis aminomethyl Guaiacol manganese chloride
(SP-5-13)-Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[6-methoxyphenolato-κO]](2-)]manganese
81065-76-1
C18H18ClMnN2O4
Inhibitors