ChemicalBook > Product Catalog >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Flufenamic acid

Flufenamic acid

Flufenamic acid Structure
CAS No.
530-78-9
Chemical Name:
Flufenamic acid
Synonyms
FA;FFA;Flufenamic;ANT-1;Arlef;ci440;CI 440;Parlef;Parlif;Saal-F
CBNumber:
CB7118092
Molecular Formula:
C14H10F3NO2
Molecular Weight:
281.23
MOL File:
530-78-9.mol
MSDS File:
SDS
Modify Date:
2024/3/19 15:37:50

Flufenamic acid Properties

Melting point 132-135 °C(lit.)
Boiling point 373.9±42.0 °C(Predicted)
Density 1.3380 (estimate)
vapor pressure 0Pa at 25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. The solubility of flufenamic acid in these solvents is approximately 11, 39, and 59 mg/ml, respectively.
pka pKa 3.9 (Uncertain);3.85 (Uncertain)
form Crystalline Powder or Chunks
color Off-white to gray-green
Water Solubility 0.0265 g/L (37 ºC)
Merck 14,4132
BRN 1996069
LogP 5.25
CAS DataBase Reference 530-78-9(CAS DataBase Reference)
NIST Chemistry Reference Flufenamic acid(530-78-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/38
Safety Statements  26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  CB4375000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29224999
Toxicity LD50 in mice: 715 mg/kg orally (Zoni)
NFPA 704
1
3 0

Flufenamic acid price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F9005 Flufenamic acid analytical standard, for drug analysis 530-78-9 10G ₹2035.1 2022-06-14 Buy
Sigma-Aldrich(India) F9005 Flufenamic acid analytical standard, for drug analysis 530-78-9 50G ₹7252.75 2022-06-14 Buy
TCI Chemicals (India) T2354 2-(3-Trifluoromethylanilino)benzoic Acid 530-78-9 25G ₹2800 2022-05-26 Buy
Product number Packaging Price Buy
F9005 10G ₹2035.1 Buy
F9005 50G ₹7252.75 Buy
T2354 25G ₹2800 Buy

Flufenamic acid Chemical Properties,Uses,Production

Chemical Properties

Fluomic acid is a Pale-Yellow or light yellow-green crystal or crystalline powder with bitter taste. It is almost insoluble in water and can be dissolved in 50% ethanol. It is a non-hormonal anti-inflammatory and analgesic drug. It was prepared by photolysis of the corresponding benzotriazinone.

Uses

Flufenamic acid is used for moderate pain and dysmenorrhea, but it should not be used for more than 1 week due to the possibility of nephrotoxicity, gastrointestinal toxicity, and anemia. It is frequently used in combination with the anticoagulant warfarin, the effect of which is strengthened when combined with flufenamic acid.

brand name

Arlef (Parke-Davis, Sankyo, Japan), Ansatin (Ono, Japan), Felunamin (Hokuriko, Japan), Romafen (Biofarma, Turkey).

Safety

Flufenamic acid is used at 600 – 800 mg/d to provide a beneficial therapeutic effect in chronic polyarthritis. The adverse effects most often encountered are gastrointestinal disturbances.

Global( 245)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Xiamen AmoyChem Co., Ltd +86-592-6051114 +8618959220845 China 6387 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
2-((3-(trifluoromethyl)phenyl)amino)-benzoicaci 2-((3-Trifluromethyl)phenyl)aminobenzoic acid Achless Acido flufenamico acidoflufenamico Ansatin ANT-1 Anthranilic acid, N-(alpha,alpha,alpha-trifluoro-m-tolyl)- Arlef Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]- C.I. 440 CI 440 TIMTEC-BB SBB001140 N-(A,A,A-TRIFLUORO-M-TOLYL)ANTHRANILIC ACID N-(ALPHA,ALPHA,ALPHA-TRIFLUOROMETHYL-M-TOLYL)ANTHRANILIC ACID N-(ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLYL)ANTHRANILIC ACID N-(3-TRIFLUOROMETHYLPHENYL)ANTHRANILIC ACID Paraflu Parlef Parlif Plostene Reumajust A Ristogen Saal-F Sastridex Surika Tecramine TVX 916 FLUFENAMIC ACID 2-(3-TRIFLUOROMETHYLANILINO)BENZOIC ACID 2-[(3-TRIFLUOROMETHYLPHENYL)AMINO]BENZOIC ACID 3'-TRIFLUOROMETHYLDIPHENYLAMINE-2-CARBOXYLIC ACID ci440 CN-27,554 CN-27544 Flufacid Flufenaminsaeure Fluore-200 Fluphenamic acid fluphenamicacid Fullsafe INF 1837 FlufenaMic acid, 97% 10GR 2-[(3-Trifluoromethylphenyl)amino]benzoic Acid 2-(3-Trifluoromethylanilino)benzoic Acid Flufenamic Acid FFA, Flufenamic acid, 3-[(2-Carboxyphenyl)amino]benzotrifluoride, 2-Carboxy-3'-(trifluoromethyl)diphenylamine inf1837 Lanceat Meralen N-((m-Trifluoromethyl)phenyl)-2-aminobenzoic acid N-(alpha,alpha,alpha-Trifluoro-m-tolyl)anthranilate n-(alpha,alpha,alpha-trifluoro-m-tolyl)-anthranilicaci n-(m-trifluoromethylphenyl)-2-aminobenzoicacid Nichisedan NSC-82699 N-(3-TRIFLUOROMETHYLPHENYL)-ANTHRANILIC& FLUFENAMIC ACID 97% FLUFENAMIC ACID MM(CRM STANDARD) Baseand/orunspecifiedsalts