SC-51322

CAS No.: 146032-79-3

Chemical Name:: SC-51322

Synonyms: SC-51322;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[3-[(2-FuranylMethyl) thio]-1-oxopropyl]hydrazide;8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacidhydrazide;Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide

CBNumber:: CB7235197

Molecular Formula:: C22H20ClN3O4S

Molecular Weight:: 457.93

MOL File:: Mol file

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

SC-51322 Properties

Melting point	112-114°C
RTECS	HQ4002000
storage temp.	Store at +4°C
solubility	DMSO: ≥10mg/mL
form	powder
color	white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301

Precautionary statements

P301+P310

Hazard Codes

Risk Statements

Safety Statements

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

HazardClass

6.1

NFPA 704

	0
2		0

SC-51322 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	PZ0132	SC-51322 ≥98% (HPLC)	146032-79-3	5MG	₹12773.5	2022-06-14	Buy
Sigma-Aldrich(India)	PZ0132	SC-51322 ≥98% (HPLC)	146032-79-3	25MG	₹51180.6	2022-06-14	Buy

Product number	Packaging	Price	Buy
PZ0132	5MG	₹12773.5	Buy
PZ0132	25MG	₹51180.6	Buy

SC-51322 Chemical Properties,Uses,Production

Description

The prostaglandin E₂ (PGE₂) receptor (EP₁) is involved in triggering PGE₂-mediated pain as well as neuronal survival and growth. SC-51322 is a selective EP₁ antagonist that inhibits PGE₂ signaling in a guinea pig ileum muscle strip assay with a pA₂ value of 8.1 and demonstrates analgesic activity in a mouse writhing assay with an ED₅₀ value of 0.9 mg/kg. It is pharmacologically similar to SC-51089, but does not release hydrazine, a known carcinogen to rats, as does SC-51089. SC-51322 potentiates the vasorelaxation of human pulmonary vein induced by PGE₂ with an EC₅₀ value of 7.75 μM.

Chemical Properties

Off-White Solid

Uses

A selective E-prostanoid receptor subtype 1 (EP1) receptor antagonist which shows antihypertensive effects.

SC-51322 Preparation Products And Raw materials

Raw materials

Preparation Products

SC-51322 Suppliers

Global( 38)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Cayman Chemical Company	(800) 364-9897	United States	6618	81	Inquiry
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	China	9707	58	Inquiry
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	China	4428	55	Inquiry
BOC Sciences	1-631-485-4226; 16314854226	United States	14059	65	Inquiry
Beijing Lebo Biotechnology Co., Ltd.	010-50934026	CHINA	6057	58	Inquiry
Shanghai Universal Biotech Co.,Ltd	18768175414	China	24998	58	Inquiry
Hubei Aiputi Bioengineering Co., Ltd.	17762444226	China	2402	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	23963	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
TargetMol Chemicals Inc.	58
Cayman Chemical Company	81
Shanghai EFE Biological Technology Co., Ltd.	58
Guangzhou Isun Pharmaceutical Co., Ltd	55
BOC Sciences	65
Beijing Lebo Biotechnology Co., Ltd.	58
Shanghai Universal Biotech Co.,Ltd	58
Hubei Aiputi Bioengineering Co., Ltd.	58
TargetMol Chemicals Inc.	58

146032-79-3(SC-51322)Related Search:

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Sulprostone PROSTAGLANDIN B1 Fluprostenol Prostaglandin F2a PROSTAGLANDIN A1

PROSTAGLANDIN B2 SC-51089 U-75302 L-161,982 6(R)-(4-CARBOXYPHENYLTHIO)-5(S)-HYDROXY-7(E),9(E),11(Z),14(Z)-EICOSATETRAENOIC ACID

11BETA-PROSTAGL AND IN F2ALPHA LEUKOTRIENE B4 DIMETHYL AMIDE LEUKOTRIENE D4

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SC-51322 8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacidhydrazide 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[3-[(2-FuranylMethyl) thio]-1-oxopropyl]hydrazide Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide 146032-79-3 Amines Heterocycles Inhibitors Intermediates & Fine Chemicals Pfizer compounds Pharmaceuticals Sulfur & Selenium Compounds