Tyramine hydrochloride
- CAS No.
- 60-19-5
- Chemical Name:
- Tyramine hydrochloride
- Synonyms
- Mydrial;Uteramin;Tyramine HCI;TyraMine hydro;TRYPTAMINE HCL;Hydrphenacetamine;TIMTEC-BB SBB000359;tyraminemonochloride;yramine hydrochloride;Tyramine hydrochloride
- CBNumber:
- CB7345058
- Molecular Formula:
- C8H12ClNO
- Molecular Weight:
- 173.64
- MOL File:
- 60-19-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/14 16:39:47
| Melting point | 253-255 °C(lit.) |
|---|---|
| Boiling point | 269°C/760mmHg |
| storage temp. | Store below +30°C. |
| solubility | H2O: soluble50 mg/ml, clear, colorless to faintly yellow |
| form | Crystalline Powder |
| color | White to almost white |
| PH | <7 (H2O) |
| Sensitive | Hygroscopic |
| Merck | 14,9835 |
| BRN | 3627058 |
| Stability | Hygroscopic |
| LogP | 0.722 (est) |
| CAS DataBase Reference | 60-19-5(CAS DataBase Reference) |
| EPA Substance Registry System | Phenol, 4-(2-aminoethyl)-, hydrochloride (60-19-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NL4375000 | |||||||||
| F | 3-8-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29222900 | |||||||||
| NFPA 704 |
|
Tyramine hydrochloride price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T2879 | Tyramine hydrochloride ≥98% | 60-19-5 | 10MG | ₹3009.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T2879 | Tyramine hydrochloride ≥98% | 60-19-5 | 5G | ₹4957.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T2879 | Tyramine hydrochloride ≥98% | 60-19-5 | 1G | ₹6040.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T2879 | Tyramine hydrochloride ≥98% | 60-19-5 | 25G | ₹7057.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T2879 | Tyramine hydrochloride ≥98% | 60-19-5 | 100G | ₹25243.9 | 2022-06-14 | Buy |
Tyramine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
Off-White to Light Yellow Powder
Occurrence
Tyramine was originally a compound isolated from ergot alkaloids and decaying animal tissue. It has pharmacological effects such as increasing blood pressure and exciting the uterus.
Uses
Tyramine hydrochloride is a sympathomimetic, the hydrochloride salt of the naturally-occurring monoamine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent but cannot cross the blood-brain barrier. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods.
Application
Tyramine hydrochloride (T-HCl) is a kind of fluorogenic substrate of peroxidase. It is a naturally occurring monoamine derived from tyrosine. Tyramine Hydrochloride has been used:
coinfused with adenosine in control subjects and patients in order to reduce leg blood flow by 50% without affecting arterial blood pressure.
labelled with fluorescence dyes (Atto 488 and Atto 655) to serve as a substrate for peroxidase in immunofluorescence analysis.
used in dimethylformamide, labelled with 5-(and-6)carboxyfluorescein, succinimidyl ester/biotin to serve as a substrate for peroxidase in tyramide signal amplification.
Neurotransmitter.
Synthesis
Tyramine [2-(p-hydroxyphenyl) ethylamine], a significant metabolite of tyrosine, enzymatic synthesis of tyramine was established by two-step biocatalytic reaction. Firstly, l-tyrosine was prepared from raw pyruvate fermentation broth under the catalysis of TPL. Pyruvate fermentation broth was simply centrifuged, and then the supernatant was diluted and used as substrate to produce l-tyrosine. Secondly, l-tyrosine was collected as starting material to synthesize tyramine by immobilized TDC cells from Lactobacillus brevis. Pyridoxal phosphate was the common coenzyme for these two enzymes.
Purification Methods
Crystallise the hydrochloride from EtOH by addition of diethyl ether, or from conc HCl. [Beilstein 3 II 355.]
Tyramine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ASCENT FINE CHEM | +91 9869071684 | Gujarat, India | 18 | 58 | Inquiry |
| Indo Amines Ltd | +91-7045592702 +91-7045592702 | Mumbai, India | 42 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Dodhia Group | +91-9619867345 +91-9619867345 | Mumbai, India | 129 | 58 | Inquiry |
| Navitus Chemicals Pvt Ltd | +91-9370559385 +91-9370559385 | Maharashtra, India | 25 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ASCENT FINE CHEM | 58 |
| Indo Amines Ltd | 58 |
| JSK Chemicals | 58 |
| Dodhia Group | 58 |
| Navitus Chemicals Pvt Ltd | 58 |
| A.J Chemicals | 58 |
| CHEMSWORTH | 30 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
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