ChemicalBook > Product Catalog >Biochemical Engineering >Condensing agent >N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
- CAS No.
- 16357-59-8
- Chemical Name:
- N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
- Synonyms
- EEDQ;2-ETHOXY-1-ETHOXYCARBONYL-1,2-DIHYDROQUINOLINE;ethyl 2-ethoxyquinoline-1(2H)-carboxylate;ethyl 2-ethoxy-1,2-dihydroquinoline-1-carboxylate;2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester;EEDQ extrapure;2-Ethoxy-1-ethoxycar;LABOTEST-BB LT00440890;EEDQ (1-ETHOXY-CARBONYL-2-ETHOXY-1,2;ETHYL 2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECA
- CBNumber:
- CB7436031
- Molecular Formula:
- C14H17NO3
- Molecular Weight:
- 247.29
- MOL File:
- 16357-59-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/2/17 9:34:25
| Melting point | 62-67 °C(lit.) |
|---|---|
| Boiling point | 125-128 °C (0.1 mmHg) |
| Density | 1.1173 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| Flash point | 125-128°C/0.1mm |
| storage temp. | 2-8°C |
| solubility | Chlorofrom (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | -1.27±0.40(Predicted) |
| form | Crystalline Powder |
| color | White to beige |
| Water Solubility | insoluble |
| Sensitive | Moisture Sensitive |
| Merck | 14,3518 |
| BRN | 533048 |
| CAS DataBase Reference | 16357-59-8(CAS DataBase Reference) |
| EPA Substance Registry System | 1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester (16357-59-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 38-36/37/38-20/21/22 | |||||||||
| Safety Statements | 22-24/25-36/37/39-26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VB2010000 | |||||||||
| F | 9-21 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29334990 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,32mg/kg (32mg/kg),Journal of Medicinal Chemistry. Vol. 14, Pg. 49, 1971. | |||||||||
| NFPA 704 |
|
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 149837 | 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline ≥99% | 16357-59-8 | 5G | ₹1363.95 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 149837 | 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline ≥99% | 16357-59-8 | 25G | ₹3918.65 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 149837 | 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline ≥99% | 16357-59-8 | 100G | ₹10294.58 | 2022-06-14 | Buy |
| ALFA India | ALF-A13724-30 | 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 99% | 16357-59-8 | 250g | ₹32786 | 2022-05-26 | Buy |
| ALFA India | ALF-A13724-18 | 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline, 99% | 16357-59-8 | 50g | ₹7954 | 2022-05-26 | Buy |
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Chemical Properties,Uses,Production
Chemical Properties
White to pale yellow solid
Uses
Peptide condensing agent with little or no racemization. Amidation coupling reagent.
Application
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline is used as a coupling agent:
In the regioselective quaternization of chitosan and its amphiphilic derivatives.
In the preparation of amide-type S-MA derivative-modified QCM sensors.
Purification Methods
Dissolve EEDQ ~180g in CHCl3, evaporate to dryness in a vacuum. Add dry Et2O (20mL) and a white solid separates on standing. Set aside for a few hours, collect the solid, wash it thoroughly with cold Et2O and dry it in a vacuum (~140g, m 63.5-65o). A further crop of solid (~25g) is obtained from the filtrate on standing overnight. [Fieser & Fieser Reagents for Organic Synthesis 2 191 1969, Belleau et al. J Am Chem Soc 90 823 1968 and 90 1651 1968, Beilstein 21/3 V 28.]
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Preparation Products And Raw materials
Raw materials
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Global( 373)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ARRKEM LIFE SCIENCES PRIVATE LIMITED | +91-8148739767 +91-8148739767 | Telangana, India | 347 | 58 | Inquiry |
| Chemphora life sciences | +91-9849979989 +91-9849979989 | Hyderabad, India | 326 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6905 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4217 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4315 | 58 | Inquiry |
| Nchem Laboratories | 08068441075Ext 386 | Hyderabad, India | 156 | 58 | Inquiry |
| Vyas Bio Life Sciences Pvt. Ltd | -65546373 | Hyderabad, India | 1213 | 58 | Inquiry |
| Sisco Resech Laboratories Private Limited | +91-22-4268 5800 | Mumbai, India | 655 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2332 | 58 | Inquiry |
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Spectrum
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline(16357-59-8)MSN-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline(16357-59-8)1HNMRN-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline(16357-59-8)13CNMRN-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline(16357-59-8)IR1N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline(16357-59-8)IR2N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline(16357-59-8)Raman
16357-59-8(N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline)Related Search:
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline≥ 99% (HPLC)
Ethyl 2-ethoxy-1,2-dihydro-1-quinolinecarboxylate for synthesis
EEDQ~N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
ethyl N-(2-ethoxy-1,2-dihydroquinoline)carboxylate
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline ,98%
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, 99+% 100GR
ETHYL 2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECA
2-Ethoxy-1-ethoxycarbonyl-1.2-dihydroquinoline 1g [16357-59-8]
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline,N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, EEDQ, Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
EEDQ, 97+% (2-ETHOXY-1-ETHOXYCARBONYL-1, 2-DIHYDROQUINOLINE)
2-Ethoxy-1-ethoxycar
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline >=99%
- ethoxy - 1-2 ethoxy carbonyl - 1, 2 - dihydro quinoline
2-ethoxy-1(2h)-quinolinecarboxylicaciethylester
1,2-Dihydro-2-ethoxy-1-(ethoxycarbonyl)quinoline, Ethyl 2-ethoxyquinoline-1(2H)-carboxylate, EEDQ
EEDQ (1-ETHOXY-CARBONYL-2-ETHOXY-1,2
EEDQ, 99+%, (2-ETHOXY-1-ETHOXYCARBONYL-1 ,2-DIHYDROQUINOLINE)
N-ETHOXYCARBONYL-2-ETHOXY-1,2-DIHYDROQUINOLINE 99% ( EEDQ)
Eedq(2-Ethoxy-1-Ethoxycarbonyl-1,2-Dihydroquinoline)
1,2-Dihydro-2-ethoxy-1-quinolinecarboxylicacidester
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, 99+%
1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester
ethoxycarbonyl-2-ethoxy-1-2-dlhdroquinoline
2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline (EEDQ)
EEDQ extrapure
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, EEDQ, Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
Ethyl 2-ethoxy-1(2H)-quinolinecarboxylate
Ethyl 2-ethoxy-2H-quinoline-1-carboxylate
N-Carbethoxy-2-ethoxy-1,2-dihydroquinoline
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline ,98.3%
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline（EEDQ）
1,2-Dihydro-2-ethoxy-1-quinolinecarboxylic acid ethyl ester
LABOTEST-BB LT00440890
ETHYL 1,2-DIHYDRO-2-ETHOXY-1-QUINOLINECARBOXYLATE
ETHYL 1,2-DIHYDRO-2-ETHOXYQUINOLINE-1-CARBOXYLATE
ETHYL 2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECARBOXYLATE
2-ETHOXY-1(2H)-QUINOLINECARBOXYLIC ACID ETHYL ESTER
2-ETHOXY-1,2-DIHYDRO-1-QUINOLINECARBOXYLIC ACID ETHYL ESTER
1-ETHOXYCARBONYL-2-ETHOXY-1,2-DIHYDROQUINOLINE
N-ETHOXYCARBONYL-2-ETHOXY-1,2-DIHYDROQUINOLINE
Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate 97+%
2-Ethoxy-N-(ethoxycarbonyl)-1,2-dihydroquinoline
EEDQ, 99+%, (2-ETHOXY-1-ETHOXYCARBONYL-1 ,2-DIHYDROQUINO
1-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline>
EEDQ 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline,99%
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline USP/EP/BP
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline 16357-59-8
ethyl 2-ethoxyquinoline-1(2H)-carboxylate
2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester
ethyl 2-ethoxy-1,2-dihydroquinoline-1-carboxylate
EEDQ
2-ETHOXY-1-ETHOXYCARBONYL-1,2-DIHYDROQUINOLINE
16357-59-8
C11H17ON3
Condensation & Active Esterification
Coupling Reactions (Peptide Synthesis)
Peptide Synthesis
Others