Fipronil
- CAS No.
- 120068-37-3
- Chemical Name:
- Fipronil
- Synonyms
- Termidor;Fipronil 95%;ipronil;Frontline Spot-on;Fluocyanobenpyrazole;5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile;REGENT;PRINCE;FIPRONIL;m&b46030
- CBNumber:
- CB7461570
- Molecular Formula:
- C12H4Cl2F6N4OS
- Molecular Weight:
- 437.15
- MOL File:
- 120068-37-3.mol
- Modify Date:
- 2024/7/2 8:55:16
| Melting point | 200-201°C |
|---|---|
| Boiling point | 510.1±50.0 °C(Predicted) |
| Density | 1.477-1.626 |
| vapor pressure | 3.7×10-7 Pa (25 °C) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO: 250 mg/mL (571.89 mM) |
| pka | -5.86±0.20(Predicted) |
| form | Solid |
| Water Solubility | 1.9-2.4 mg 1l-1 (20 °C） |
| color | White to Light yellow |
| λmax | 208nm(H2O)(lit.) |
| Merck | 14,4085 |
| BRN | 8090115 |
| LogP | 4.000 |
| CAS DataBase Reference | 120068-37-3(CAS DataBase Reference) |
| EPA Substance Registry System | Fipronil (120068-37-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H372-H410 | |||||||||
| Precautionary statements | P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314 | |||||||||
| Hazard Codes | T,N | |||||||||
| Risk Statements | 23/24/25-48/25-50/53-55-57-36 | |||||||||
| Safety Statements | 26-36/37/39-45-60-61-36/37-28 | |||||||||
| RIDADR | 2588 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UQ4430250 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29331990 | |||||||||
| Toxicity | LD50 in rats (mg/kg): 100 orally; >2000 dermally (Colliot); in mice (mg/kg): 32 i.p. (Cole) | |||||||||
| NFPA 704 |
|
Fipronil price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 46451 | Fipronil PESTANAL?, analytical standard | 120068-37-3 | 100MG | ₹19896.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 16785 | Fipronil certified reference material, TraceCERT? | 120068-37-3 | 50MG | ₹11496.15 | 2022-06-14 | Buy |
| TCI Chemicals (India) | F0822 | Fipronil min. 97.0 % | 120068-37-3 | 1G | ₹8100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | F0822 | Fipronil min. 97.0 % | 120068-37-3 | 5G | ₹15000 | 2022-05-26 | Buy |
Fipronil Chemical Properties,Uses,Production
Description
Fipronil is a white powder with a mouldy odour. It has a low solubility in water and is a slow-acting poison. It does not bind strongly with soil, and the half-life of fipronil– sulphone is 34 days. Fipronil is a broadspectrum insecticide of the phenylpyrazole group. Fipronil was first used extensively for the control of ants, beetles, cockroaches, fleas; ticks, termites, mole crickets, thrips, rootworms, weevils, flea of pets, field pest of corn, golf courses, and commercial turf, and other insects. Fipronil was first used in the United States in 1996. Fipronil is a topical insecticide. It kills adult fleas and larvae, ticks, and chewing lice. As a liquid, fipronil is applied on the back side skin of dogs and cats. Reports indicate that some animals do become hypersensitive (allergic) to fipronil.
Chemical Properties
White SOlid
Uses
Fipronil is used for the control of a wide range of insect species in rice, cereals, corn, cotton, top fruit, sugar beet, sugar cane, oilseed rape, many vegetables and other high-value crops. It also has a veterinary use as an ectoparasiticide.
Agricultural Uses
Insecticide, Veterinary medicine: Not approved for use in EU countries. Fipronil was introduced into the U.S. in 1996 for use in animal health and indoor pest control. It is the constituent of many products for controlling a wide spectrum of domestic animal and residential pests.
Trade name
BES® 602; CEASEFIRE®; CHIPCO®; COMBAT®; FRONTLINE; MB-46030®; H&G®; ICON®; MAXFORCE® ANT STATION; MAXFORCE® ROACH STATION; REGENCY SOFION®; REGENT®; REGENT® 500-FS; TERMIDOR® L VI-NIL
Pharmacology
Fipronil is a phenylpyrazole, the mode of action of which
is to inhibit nerve transmission in arthropods by blocking
γ -aminobutyric acid-gated chloride channels. Fipronil is
available as spray and spot-on formulations to control
fleas and ticks on cats and dogs. The adulticidal activity of
fipronil accounts for the majority of its activity, although
additional activity against flea eggs and larvae results
from the presence of fipronil on hairs and debris shed into
the environment from treated pets.
Autohistoradiography studies (11) into the cutaneous
distribution of 14C-fipronil in the cat and dog following
spot-on administration demonstrated that radioactivity
was restricted principally to the stratum corneum, the
viable epidermis, and the pilosebaceous units. Following
its slow release from sebaceous glands, fipronil migrates in
the sebum covering the skin and hairs by passive diffusion
and was shown to persist on hair for up to 2 months after
treatment.
Potential Exposure
Pyrazole/phenylpyrazole/organofluor ine insecticide; veterinary medicine. Fipronil was intro duced into the United States in 1996 for use in animal health and indoor pest control. It is the constituent of many products for controlling a wide spectrum of domestic ani mal and residential pests. Banned for use in EU.
Metabolic pathway
Through the abiotic degradation of fipronil in aqueous solution and on the soil surface, 5-amino-3- carbamoyl-1-[2,6-dichloro-4-(trifluoromethyl)-phenyl]-4- [(trifluoromethyl)sulfinyl]pyrazole is the only hydrolysis product detected. Fipronil in acidic aqueous solution exposed under a xenon lamp degrades with the concomitant appearance of 5-amino-3-cyano-1-[2,6- dichloro-4-(trifluoromethyl)-phenyl]-4- (trifluoromethyl)pyrazole and 5-amino-3-cyano-1-[2,6- dichloro-4-(trifluoromethyl)phenyl]pyrazole-4-sulfonic acid. Under field conditions, when fipronil is applied in formulation, four metabolites which include one product resulting from reduction on the sulfur atom of fipronil are detected.
Shipping
UN2588 Pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN2902 Pesticide, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Waste Disposal
It is the responsibility of chemical waste generators to determine the toxicity and physical properties and of a discarded chemical and to properly identify its classification and certification as a haz ardous waste and to determine the disposal method. United States Environmental Protection Agency guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult and fol low all regional, national, state and local hazardous waste laws to ensure complete and accurate classification and dis posal methods.
Fipronil Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Gharda Chemicals Ltd | +919820134485 | Maharashtra, India | 32 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Bharat Rasayan | +91-9619772584 +91-9619772584 | Maharashtra, India | 23 | 58 | Inquiry |
| Kilpest India limited | +91-7552586536 +91-7552586536 | Madhya Pradesh, India | 38 | 58 | Inquiry |
| ENTOMIC CHEMICALS | +91-9425149263 +91-9425149263 | Madhya Pradesh, India | 39 | 58 | Inquiry |
| Crimsun Organics PvtLtd | +91-4142239777 +91-4142239777 | Tamil Nadu, India | 4 | 58 | Inquiry |
| General Crop Science | +91-9810438260 +91-9896700555 | Haryana, India | 31 | 58 | Inquiry |
| SD Agro Chemicals | +91-9650182828 +91-9871331171 | Uttar Pradesh, India | 42 | 58 | Inquiry |
| Krishi Rasayan Exports Pvt Ltd | +91-3371081010 +91-3371081012 | West Bengal, India | 12 | 58 | Inquiry |
| Shogun Organics Ltd | +91-2266776846 +91-2266776845 | Maharashtra, India | 8 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Gharda Chemicals Ltd | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
| Bharat Rasayan | 58 |
| Kilpest India limited | 58 |
| ENTOMIC CHEMICALS | 58 |
| Crimsun Organics PvtLtd | 58 |
| General Crop Science | 58 |
| SD Agro Chemicals | 58 |
| Krishi Rasayan Exports Pvt Ltd | 58 |
| Shogun Organics Ltd | 58 |
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