Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >GSK-3 inhibitors >4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE Structure
CAS No.
327036-89-5
Chemical Name:
4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE
Synonyms
CS-568;NP 01139;TDZD-8/TDZD8;TDZD-8, >=98%;TDZD-8 (NP-01139);GSK-3β Inhibitor I;GSK-3InhibitorI,TDZD-8;TDZD-8;TDZD 8;TDZD8;NP 01139;TDZD8; TDZD 8;GSK-3Β) INHIBITOR I; NP 01139;GSK-3β Inhibitor I - CAS 327036-89-5 - Calbiochem
CBNumber:
CB7501586
Molecular Formula:
C10H10N2O2S
Molecular Weight:
222.26
MOL File:
327036-89-5.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE Properties

Melting point 63-64.4 °C
Boiling point 335.5±35.0 °C(Predicted)
Density 1.375±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 18 mg/mL
pka -2.08±0.20(Predicted)
form needles
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P342+P311
Hazard Codes  Xi
Risk Statements  43
Safety Statements  36/37
WGK Germany  3
HS Code  2934999090
NFPA 704
0
2 0

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T8325 TDZD-8 ≥98% (HPLC), needles 327036-89-5 5MG ₹15966.88 2022-06-14 Buy
Sigma-Aldrich(India) T8325 TDZD-8 ≥98% (HPLC), needles 327036-89-5 25MG ₹57545.7 2022-06-14 Buy
Sigma-Aldrich(India) 361540 GSK-3β Inhibitor I - CAS 327036-89-5 - Calbiochem The GSK-3β Inhibitor I, also referenced under CAS 327036-89-5, controls the biological activity of GSK-3β. This small molecule/inhibitor is primarily 327036-89-5 5MG ₹15469.99 2022-06-14 Buy
TCI Chemicals (India) B4436 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione 327036-89-5 5MG ₹6800 2022-05-26 Buy
TCI Chemicals (India) B4436 4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione 327036-89-5 25MG ₹14000 2022-05-26 Buy
Product number Packaging Price Buy
T8325 5MG ₹15966.88 Buy
T8325 25MG ₹57545.7 Buy
361540 5MG ₹15469.99 Buy
B4436 5MG ₹6800 Buy
B4436 25MG ₹14000 Buy

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selectiv

General Description

A cell-permeable, thiadiazolidinone (TDZD) analog that acts as a highly selective, non-ATP-competitive inhibitor of GSK-3β (IC50 = 2 μM). Inhibits Flt-3 and PKC activities (IC50 = 673 nM and 1.4-5.5 μM, respectively). Does not significantly affect the activities of Cdk1/cyclin B, CK-II, PKA, or PKC (IC50 >100 μM). Shown to inhibit collagen- and thrombin-induced platelet aggregation.

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE Suppliers

Global( 133)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd +8613580539051 CHINA 21149 58 Inquiry
Supplier Advantage
TCI Chemicals (India) Pvt. Ltd. 58
A.J Chemicals 58
Capot Chemical Co.,Ltd. 60
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 58

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE Spectrum

4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE(327036-89-5)1HNMR

327036-89-5(4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE)Related Search:

AR-A014418 Ethacrynic acid SB 415286 1-AZAKENPAULLONE KAHWEOL
SEDANOLIDE S-[N-(3-PHENYLPROPYL)(THIOCARBAMOYL)]-L-CYSTEINE CAFESTOL 2-THIO(3-IODOBENZYL)-5-(1-PYRIDYL)-[1,3,4]-OXADIAZOLE SB216763
Belnacasan (VX-765) Bosutinib Saracatinib Tideglusib Z-VAD-FMK
TDZD-8 TD 139 MANZAMINE A
chevron_left

1of4

chevron_right
GSK-3InhibitorI,TDZD-8 NP 01139 1,2,4-Thiadiazolidine-3,5-dione,2-Methyl-4-(phenylMethyl)- TDZD-8/TDZD8 4-Benzyl-2-methyl-[1,2,4]thiadiazolidine-3,5-dione TDZD-8 TDZD-8, >=98% TDZD-8;TDZD 8;TDZD8;NP 01139 2-Methyl-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione GSK-3β Inhibitor I - CAS 327036-89-5 - Calbiochem CS-568 TDZD8; TDZD 8;GSK-3Β) INHIBITOR I; NP 01139 TDZD-8 (NP-01139) GSK-3β Inhibitor I inhibit,TDZD8,Inhibitor,TDZD 8,NP01139,GSK-3,TDZD-8,Glycogen synthase kinase 3,NP-01139,Glycogen synthase kinase-3 327036-89-5 Amines Aromatics Sulfur & Selenium Compounds Other Enzyme Inhibitors and Activators. Inhibitors Akt mTOR PI3K