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ChemicalBook > Product Catalog >API >Antineoplastic agents >Tinib Antineoplastic drugs >Octenidine dihydrochloride

Octenidine dihydrochloride

Octenidine dihydrochloride Structure
CAS No.
70775-75-6
Chemical Name:
Octenidine dihydrochloride
Synonyms
Octenidine hydrochloride;SOT360;Octenidine DiHCl;Otinidine hydrochloride;ocenidine dihydrochloride;OCTENIDINE DIHYDROCHLORIDE;Ortinidine dihydrochloride;TRANS-2-NONENAL 18829-56-6;OctenidineDihydrochloride>Octenidine dihydrochloride 97%
CBNumber:
CB7879838
Molecular Formula:
C36H64Cl2N4
Molecular Weight:
623.82616
MOL File:
70775-75-6.mol
Modify Date:
2024/10/12 18:14:22
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Octenidine dihydrochloride Properties

Melting point 215-217℃
Density 1.046[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in dimethyl sulfoxide and methanol.
form Solid
color White to Off-White
Water Solubility 14.2g/L at 20℃
Merck 14,6754
Stability Hygroscopic
InChI InChI=1S/C36H62N4.2ClH/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;;/h23-26,31-34H,3-22,27-30H2,1-2H3;2*1H
InChIKey SMGTYJPMKXNQFY-UHFFFAOYSA-N
SMILES [N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]
LogP 1.5 at 23℃

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280-P301+P312-P362+P364
HS Code  2933399990
NFPA 704
1
2 0

Octenidine dihydrochloride price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) O0388 Octenidine Dihydrochloride 70775-75-6 1G ₹2900 2022-05-26 Buy
TCI Chemicals (India) O0388 Octenidine Dihydrochloride 70775-75-6 5G ₹9000 2022-05-26 Buy
Product number Packaging Price Buy
O0388 1G ₹2900 Buy
O0388 5G ₹9000 Buy

Octenidine dihydrochloride Chemical Properties,Uses,Production

Description

The antiseptic agent octenidine dihydrochloride (OCT) was developed by Sterling Winthrop (WIN41464-2) in the 1980s as an alternative to the anti-plaque agent CHX and successfully tested in vitro and in vivo. OCT has a broad spectrum of activity with similar effectiveness against Gram-negative and Gram-positive bacteria, fungi, and yeasts. Moreover, it has been shown that it may effectively interfere with the co-aggregation of dental plaque microbial colonizers without disturbing the normal, healthy oral flora. In a standardized comparison of antimicrobial activity ofthe antiseptic agents triclosan, polyvinylpyrrolidone-iodine, OCT, polyhexamethylene biguanide, and Chlorhexidine digluconat (CHX) using the min-imal effective concentration and minimum bactericidal con-centration, OCT was the most effective active agent of alltested antimicrobial substances. In other studies, the antibacterial and antiplaque efficacy of OCT was equal to or even greater than that of CHX[1].

Uses

Octenidine dihydrochloride is used as a antiseptic for skin, mucous Membranes and wounds.

Application

Octenidine dihydrochloride is a cationic antiseptic that belongs to the bispyridine class of chemicals. Its action is binding to anionic structures of the cell membrane, further bursting the membrane. It has activity against Gram-positive and Gram-negative bacteria. It was effective in oral hygiene, preventing plaque and gingivitis, as a whole body wash for methicillin-resistant S. aureus decolonization and skin disinfection of premature newborn infants. Octenidine concentrations of less than 1.5 μM (0.94 μg/mL) reduced each microbial population by more than 99% within 15 minutes. Staphylococcus epidermidis was the most susceptible of the test organisms, and E. coli and Candida albicans were the least susceptible. Octenidine was more active than chlorhexidine against each test strain. This antiseptic has not been established in veterinary medicine for skin preparation but is used for wound cleansing.

References

[1] A. Welk. “Antibacterial and antiplaque efficacy of a commercially available octenidine-containing mouthrinse.” Clinical Oral Investigations 20 1 (2015): 1469–1476.

Octenidine dihydrochloride Preparation Products And Raw materials

Raw materials

OCTYLAMINE HYDROCHLORIDE N-octylpyridin-4-amine 1,10-Dichlorodecane 4-Aminopyridine

Preparation Products

Octenidine dihydrochloride Suppliers

Global( 270)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
R N Laboratories Pvt Ltd 26472226736677 Maharashtra, India 10 58 Inquiry
Belchem Industries Private Limited +91-2224102288 +91-2224102278 Maharashtra, India 17 58 Inquiry
Unilab Company +91-912228260263 +91-63917864522 Tamil Nadu, India 43 58 Inquiry
JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
Dishman Carbogen Amcis Ltd (Dishman Group) +91-2717420100 +91-8154017093 Gujarat, India 90 58 Inquiry
Bajaj Healthcare Ltd +91-2266177400 +91-2266177400 Maharashtra, India 86 58 Inquiry
Centaur Pharmaceuticals Pvt Ltd +912266499100 Mumbai, India 33 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Supplier Advantage
R N Laboratories Pvt Ltd 58
Belchem Industries Private Limited 58
Unilab Company 58
JSK Chemicals 58
Dishman Carbogen Amcis Ltd (Dishman Group) 58
Bajaj Healthcare Ltd 58
Centaur Pharmaceuticals Pvt Ltd 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Triveni chemicals 58

Octenidine dihydrochloride Spectrum

Octenidine dihydrochloride(70775-75-6)MS

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