DICHLORPHENAMIDE
- CAS No.
- 120-97-8
- Chemical Name:
- DICHLORPHENAMIDE
- Synonyms
- cb8000;CB 8000;Oralcon;Glaucor;glaucol;Oratrol;Dalanide;daramide;Daranide;Dasanide
- CBNumber:
- CB8129776
- Molecular Formula:
- C6H6Cl2N2O4S2
- Molecular Weight:
- 305.16
- MOL File:
- 120-97-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:12
Melting point | 239-241° (patent, mp 228.5-229°) |
---|---|
Boiling point | 590.5±60.0 °C(Predicted) |
Density | 1.7263 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | Acetonitrile (Slightly), Chloroform, DMSO (Slightly), Methanol |
form | Solid |
pka | pKa 7.4 (Uncertain);8.6 (Uncertain) |
color | White to Off-White |
CAS DataBase Reference | 120-97-8(CAS DataBase Reference) |
NIST Chemistry Reference | 4,5-Dichloro-m-benzenedisulfonamide(120-97-8) |
EPA Substance Registry System | 1,3-Benzenedisulfonamide, 4,5-dichloro- (120-97-8) |
DICHLORPHENAMIDE Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Like the drugs described above, dichlorphenamide is used for secreting excess water in cases of elevated intraocular pressure, and it is used for treating wide-angle and secondary glaucoma as well as in cases where it is necessary to lower intraocular pressure before surgical intervention in severe wide-angle glaucoma.
Definition
ChEBI: A sulfonamide that is benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraoc lar pressure. It is used for the treatment of glaucoma.
Clinical Use
Dichlorphenamide is a disulfonamide derivative that shares the same pharmacological properties。The dose of dichlorphenamide is 25 to 100 mg one to three times a day.
DICHLORPHENAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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Nuray Chemicals Pvt Ltd | +91-4066616700 +91-8220444745 | Tamil Nadu, India | 49 | 58 | Inquiry |
Aruvi Labs | +91-8056181939 +91-8056181939 | Tamil Nadu, India | 149 | 58 | Inquiry |
Biophore India Pharmaceuticals Pvt Ltd | +91-9100031592 +91-9030907714 | Telangana, India | 134 | 58 | Inquiry |
AKASH PHARMA EXPORTS | +91-9388123451 +91-9846039283 | Kerela, India | 470 | 58 | Inquiry |
BIOPHORE INDIA PHARMACEUTICALS PVT LTD | +91-4047474545 | New Delhi, India | 105 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
AUROBINDO PHARMA LTD | +91 (40) 6672 1200 | New Delhi, India | 209 | 58 | Inquiry |