TRICHOSTATIN A
- CAS No.
- 58880-19-6
- Chemical Name:
- TRICHOSTATIN A
- Synonyms
- TSA;A 300I;CS-210;CS-2704;trichostatin;richostatinA;TRICHOSTATIN A;(R)-Trichostatin A;(+)-Trichostatin A;Trichostatin A (TSA)
- CBNumber:
- CB8257301
- Molecular Formula:
- C17H22N2O3
- Molecular Weight:
- 302.37
- MOL File:
- 58880-19-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/17 16:57:51
| Melting point | 140-143℃ |
|---|---|
| alpha | D20.5 +62.8° ±1.1° (c = 1.007 in ethanol) |
| Density | 1.139 |
| refractive index | 136 ° (C=0.3, MeOH) |
| storage temp. | -20°C |
| solubility | ethanol: 1 mg/mL |
| pka | 8.93±0.23(Predicted) |
| form | Off-white lyophilized solid |
| color | Tan |
| Merck | 14,9649 |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| InChIKey | ZWGICMNKJBUOHG-RCXLNATQSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H317-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 20/21/22-36/37/38-43 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | NA 1993 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | MI5215000 | |||||||||
| HS Code | 29280000 | |||||||||
| NFPA 704 |
|
TRICHOSTATIN A price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | V900931 | Trichostatin A Vetec?, reagent grade, from Streptomyces sp., ≥98% | 58880-19-6 | 1MG | ₹21834.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | V900931 | Trichostatin A Vetec?, reagent grade, from Streptomyces sp., ≥98% | 58880-19-6 | 5MG | ₹40041.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8552 | Trichostatin A ≥98% (HPLC), from Streptomyces sp. | 58880-19-6 | 1MG | ₹24832.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T8552 | Trichostatin A ≥98% (HPLC), from Streptomyces sp. | 58880-19-6 | 5MG | ₹82811.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T1952 | Trichostatin A, Ready Made Solution 5?mM in DMSO (0.2 μm-filtered), from Streptomyces sp. | 58880-19-6 | 200μL | ₹7820.4 | 2022-06-14 | Buy |
TRICHOSTATIN A Chemical Properties,Uses,Production
Chemical Properties
Solid
Uses
Trichostatin A is a known inhibitor of fibrosis in vitro and in vivo, and is used as an anticancer agent. Potent differentiation inducer of friend leukemic cells.
General Description
Trichostatin A is a compound of primary hydroxamic acid.
Biological Activity
Selective and potent inhibitor of histone deacetylase (K i = 3.4 nM). Active in vivo . Potential anti-cancer agent. Induces accelerated dedifferentiation of primordial germ cells (PGCs) into embryonic germ (EG) cells.
TRICHOSTATIN A Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 230)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TRC FINE CHEMS | +91-7400278327 +91-8097105248 | Mumbai, India | 73 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16920 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9336 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29896 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
58880-19-6(TRICHOSTATIN A)Related Search:
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7-(4-(dimethylamino)phenyl)-n-hydroxy-4,6-dimethyl-7-oxo-4-heptadienamide
7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE
4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXAHEPTA-2,4-DIENOHYDROXAMIC ACID
4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXOHEPTA-2,4-DIENOHYDROXAMIC ACID
Trichostatin A from Streptomyces platensis
[r-(e,e)]-7-[4-(dimethylamino)phenyl]-n-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE
TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
TRICHOSTATIN A
TRICHOSTATIN A, STREPTOMYCES SPECIES
Trichostatin A, Streptomyces sp.
2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
TRICHOSTATIN A FROM STREPTOMYCES SP
(2E,4E,6R)-4,6-Dimethyl-7-[4-(dimethylamino)phenyl]-7-oxo-2,4-heptadienehydroximic acid
(2E,4E,6R)-4,6-Dimethyl-7-oxo-7-[4-(dimethylamino)phenyl]-2,4-heptadienehydroximic acid
Trichostatin A,TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
(R)-Trichostatin A
A 300I
(R,2E,4E)-6-(4-(dimethylamino)benzoyl)-N-hydroxy-4-methylhepta-2,4-dienamide
Trichostatin A, Ready Made Solution
Trichostatin A Vetec(TM) reagent grade, from Streptomyces sp., >=98%
(2E,4E,6R)-7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE
Trichostatin A (TSA)
(R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
trichostatin
TRICHOSTATIN A USP/EP/BP
richostatinA
isolated from species of the bacterial genus Streptomyces.
CS-210
CS-2704
Trichostatin A, 98%, from Streptomyces sp.
TSA
Histone deacetylases,inhibit,Inhibitor,HDAC,Trichostatin A
Trichostatin A solution(10mM/L)
(+)-Trichostatin A
Trichostatin A (R-isomer)
58880-19-6
5880-19-6
Gene Regulation and Expression
DNA-RNA Transcription Regulators
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Inhibitors
antibiotic
API
Anti Cancer Research
Inhibitor