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NU7026

CAS No.: 154447-35-5

Chemical Name:: NU7026

Synonyms: CS-595;LY 293646;NU7026, >=98%;NU 7026; NU-7026;NU7026 USP/EP/BP;NU7026;LY293646; NU-7026;DNA-PK Inhibitor II NU7026 NU-7026;2-MORPHOLINO-4H-BENZO[H]CHROMEN-4-ONE;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one;2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one

CBNumber:: CB8503981

Molecular Formula:: C17H15NO3

Molecular Weight:: 281.31

MOL File:: 154447-35-5.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

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NU7026 Properties

Melting point	267-269 °C(Solv: methanol (67-56-1); water (7732-18-5))
Boiling point	459.9±45.0 °C(Predicted)
Density	1.330
storage temp.	2-8°C
solubility	DMSO: 3 mg/mL at 60 °C, soluble
form	solid
pka	0.49±0.20(Predicted)
color	tan

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05
Signal word	Danger
Hazard statements	H314
Precautionary statements	P501-P264-P280-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P405
WGK Germany	3

NU7026 price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	N1537	NU7026 ≥98% (HPLC), solid	154447-35-5	5MG	₹27365.6	2022-06-14	Buy
Sigma-Aldrich	260961	DNA-PK Inhibitor II - CAS 154447-35-5 - Calbiochem The DNA-PK Inhibitor II, also referenced under CAS 154447-35-5, controls the biological activity of DNA-PK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation appl	154447-35-5	5MG	₹28240	2022-06-14	Buy
Sigma-Aldrich(India)	260961	DNA-PK Inhibitor II - CAS 154447-35-5 - Calbiochem The DNA-PK Inhibitor II, also referenced under CAS 154447-35-5, controls the biological activity of DNA-PK. This small molecule/inhibitor is primarily	154447-35-5	5MG	₹28240	2022-06-14	Buy

Product number	Packaging	Price	Buy
N1537	5MG	₹27365.6	Buy
260961	5MG	₹28240	Buy
260961	5MG	₹28240	Buy

NU7026 Chemical Properties,Uses,Production

Uses

NU7026 has been used:

as a DNA-dependent protein kinase (DNA-PK) inhibitor, to pre-treat colon cancer cell
in kinase inhibitor experiments for treating zygotes with visible pronuclei post 20 h-human chorionic gonadotropin (hCG)
to determine its influence on cytotoxicity of dibenzo[def,p]chrysene on HepG2 cells

Biological Activity

ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC 50 values are 0.23, 13.0, > 100 and > 100 μ M for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair.

Biochem/physiol Actions

Cell permeable, small molecule benzochromenone inhibitor of DNA-PK (DNA dependent protein kinase).

NU7026 Preparation Products And Raw materials

Raw materials

N-Acetylmorpholine METHYL 1-HYDROXY-2-NAPHTHOATE 1-(1-hydroxynaphthalen-2-yl)-3-Morpholin-4-ylpropane-1,3-dione

Preparation Products

NU7026 Suppliers

Global( 107)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	26368	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	China	11681	58	Inquiry
Young Lively PharminBlock Co.,Ltd	+undefined18600731423	China	1944	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Young Lively PharminBlock Co.,Ltd	58
Aladdin Scientific	58

NU7026 Spectrum

NU7026(154447-35-5)¹HNMR

154447-35-5(NU7026)Related Search:

Imidazolidinyl urea NU7441 (KU-57788) KU-55933 (ATM Kinase Inhibitor) VE-821 KU-60019

ABT 737 Olaparib NU7026 4H-1-Benzopyran-4-one, 2-(diethylamino)-

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2-MORPHOLINO-4H-BENZO[H]CHROMEN-4-ONE NU7026, >=98% 2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one NU7026;LY293646; NU-7026 LY 293646 2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one 4H-Naphtho[1,2-b]pyran-4-one, 2-(4-morpholinyl)- 2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one NU7026 DNA-PK Inhibitor II - CAS 154447-35-5 - Calbiochem NU 7026; NU-7026 CS-595 NU7026 USP/EP/BP DNA-PK Inhibitor II NU7026 NU-7026 DNA-dependent protein kinase,inhibit,NU-7026,Apoptosis,DNA-PK,LY-293646,Inhibitor,LY 293646,NU 7026 154447-35-5 Inhibitors