ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Nuclear transcription factor (NF-κB) >NF-κB inhibitor >4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Structure
CAS No.
749886-87-1
Chemical Name:
4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE
Synonyms
JSH-23;CS-1344;JSH-23 HCL;JSH-23;JSH23;JSH 23;NF-κB Activation Inhibitor II;NFκB Activation Inhibitor II, JSH-23;4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE;4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine;4-methyl-1-N-(3-phenylpropyl)benzene-1,2-diamine;JSH-23;JSH23;JSH 23;NF-ΚB ACTIVATION INHIBITOR II
CBNumber:
CB8649474
Molecular Formula:
C16H20N2
Molecular Weight:
240.34
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2023/6/8 17:06:35

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Properties

Melting point 104.4-105.0℃
Boiling point 418.7±40.0 °C(Predicted)
Density 1.086±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: >10mg/mL
pka 5.99±0.11(Predicted)
form solid
color off-white to gray-pink

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302-H318-H400
Precautionary statements  P273-P280-P305+P351+P338
Hazard Codes  Xn,N
Risk Statements  22-41-50/53
Safety Statements  26-39-60-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
HS Code  2921.59.8090
NFPA 704
0
3 0

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) J4455 JSH-23 ≥98% (HPLC), solid 749886-87-1 5MG ₹17601.45 2022-06-14 Buy
Sigma-Aldrich(India) J4455 JSH-23 ≥98% (HPLC), solid 749886-87-1 25MG ₹70005.28 2022-06-14 Buy
TCI Chemicals (India) M2734 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine min. 98.0 % 749886-87-1 25MG ₹9000 2022-05-26 Buy
TCI Chemicals (India) M2734 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine min. 98.0 % 749886-87-1 100MG ₹18200 2022-05-26 Buy
Product number Packaging Price Buy
J4455 5MG ₹17601.45 Buy
J4455 25MG ₹70005.28 Buy
M2734 25MG ₹9000 Buy
M2734 100MG ₹18200 Buy

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Chemical Properties,Uses,Production

Uses

A cell-permeable, selective blocker of nuclear translocation of NF-KB p65. NF-KB activation inhibitor II, JSH-23

General Description

A cell-permeable diamino compound that selectively blocks nuclear translocation of NF-κB p65 and its transcription activity (IC50 = 7.1 μM in a NF-κB reporter assay using RAW 264.7) without affecting IκB degradation. Shown to suppress DNA-binding of NF-κB and downregulate LPS-induced gene expression and apoptotic chromatin condensation.

Biochem/physiol Actions

Primary TargetBlocks nuclear translocation of NF-κB p65 and its transcription activity

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 114)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26165 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
Coresyn Pharmatech Co., Ltd. +86-571-86626709 +86-18157142896 China 9991 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Spectrum

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE JSH-23 4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine 4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine JSH 23 JSH 23 4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine NFκB Activation Inhibitor II, JSH-23 JSH-23;JSH23;JSH 23;NF-ΚB ACTIVATION INHIBITOR II NF-κB Activation Inhibitor II 4-methyl-1-N-(3-phenylpropyl)benzene-1,2-diamine JSH-23;JSH23;JSH 23 CS-1344 NF-κB Activation Inhibitor II, JSH-23 - CAS 749886-87-1 - Calbiochem 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine> 1,2-Benzenediamine, 4-methyl-N1-(3-phenylpropyl)- 4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE USP/EP/BP JSH-23 HCL Nuclear factor-κB,Nuclear factor-kappaB,JSH-23,NF-κB,JSH23,JSH 23,Inhibitor,inhibit JSH-23, 98%, an NF-κB inhibitor which inhibits NF-κB transcriptional activity 749886-87-1 Chemical Amines Amines Aromatics Inhibitors