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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Nuclear transcription factor (NF-κB) >NF-κB inhibitor >4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE

4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Structure
  • ₹9000 - ₹70005.28
  • Product name: 4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE
  • CAS: 749886-87-1
  • MF: C16H20N2
  • MW: 240.34
  • EINECS:
  • MDL Number:MFCD09753595
  • Synonyms:4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE;JSH-23;4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine;4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine JSH 23;JSH 23 4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine;4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine;NFκB Activation Inhibitor II, JSH-23;JSH-23;JSH23;JSH 23;NF-ΚB ACTIVATION INHIBITOR II
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberM2734
  • Product description4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine min. 98.0 %
  • Packaging25MG
  • Price₹9000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2734
  • Product description4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine min. 98.0 %
  • Packaging100MG
  • Price₹18200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberJ4455
  • Product descriptionJSH-23 ≥98% (HPLC), solid
  • Packaging25MG
  • Price₹70005.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberJ4455
  • Product descriptionJSH-23 ≥98% (HPLC), solid
  • Packaging5MG
  • Price₹17601.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M2734 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine min. 98.0 % 25MG ₹9000 2022-05-26 Buy
TCI Chemicals (India) M2734 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine min. 98.0 % 100MG ₹18200 2022-05-26 Buy
Sigma-Aldrich(India) J4455 JSH-23 ≥98% (HPLC), solid 25MG ₹70005.28 2022-06-14 Buy
Sigma-Aldrich(India) J4455 JSH-23 ≥98% (HPLC), solid 5MG ₹17601.45 2022-06-14 Buy

Properties

Melting point :104.4-105.0℃
Boiling point :418.7±40.0 °C(Predicted)
Density :1.086±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: >10mg/mL
pka :5.99±0.11(Predicted)
form :solid
color :off-white to gray-pink

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

JSH-23 is an inhibitor of NF-κB, blocking its translocation into the nucleus (IC50 = 7.1 μM). It does not affect degradation of the inhibitor of NF-κB, IκB. JSH-23 interferes with NF-κB-mediated gene expression and apoptosis in RAW 264.7 cells treated with lipopolysaccharide. It has also been used to investigate the roles of NF-κB in cancer, inflammation, and neurogenesis.

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Suppliers and manufacturers

career henan chemical co
4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE
₹9.80 /1.79999995231628KG
4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE CAS:749886-87-1
A.J Chemicals TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
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Dideu Industries Group Limited
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