ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Urine (urea) pyrimidine >Trifluorothymine
Trifluorothymine
- CAS No.
- 54-20-6
- Chemical Name:
- Trifluorothymine
- Synonyms
- 5-(TRIFLUOROMETHYL)URACIL;TRIFLUOROMETHYLURACIL;5-(trifluoroMethyl)pyriMidine-2,4-diol;5-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione;5-Trifluoromethyl;2,4-DIHYDROXY-5-TRIFLUOROMETHYL-1H-PYRIMIDINE;L 595725-0-1;TRIFLUOROTHYMINE;5-Trifluorothymine;Trifluorothymine 5-
- CBNumber:
- CB8684875
- Molecular Formula:
- C5H3F3N2O2
- Molecular Weight:
- 180.08
- MOL File:
- 54-20-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/9 22:15:29
| Melting point | 245-246 °C(lit.) |
|---|---|
| Density | 1.5484 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | methanol: soluble50mg/mL, clear |
| form | powder to crystal |
| pka | 6.63±0.10(Predicted) |
| color | White to Orange to Green |
| Water Solubility | INSOLUBLE |
| BRN | 612694 |
| InChIKey | LMNPKIOZMGYQIU-UHFFFAOYSA-N |
| CAS DataBase Reference | 54-20-6(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,4(1H,3h)-pyrimidinedione, 5-(trifluoromethyl)-(54-20-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 22-36/38-40-36/37/38-25 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | YR1750000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | Ⅲ | |||||||||
| HS Code | 29335990 | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: 800mg/kg | |||||||||
| NFPA 704 |
|
Trifluorothymine price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 223271 | Trifluorothymine 97% | 54-20-6 | 250MG | ₹2608.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 223271 | Trifluorothymine 97% | 54-20-6 | 250MG | ₹2608.83 | 2022-06-14 | Buy |
| TCI Chemicals (India) | T1622 | 5-(Trifluoromethyl)uracil | 54-20-6 | 1G | ₹4700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | T1622 | 5-(Trifluoromethyl)uracil | 54-20-6 | 5G | ₹15200 | 2022-05-26 | Buy |
Trifluorothymine Chemical Properties,Uses,Production
Chemical Properties
White to faintly yellow crystalline powder
Application
Trifluorothymine (5-(Trifluoromethyl)uracil) is an application medicine intermediate widely. It may be used for the synthesis of the cancer therapy drug trifluridine and also can be used for the preparation of the 2, 4-dichloro-5-trifluoromethyluracil.
Synthesis
Uracil and sodium triflate can be used as raw materials to synthesize Trifluorothymine. This reaction uses a mixed solvent of methylene chloride and water as the reaction solvent and tert-butyl hydroperoxide as the catalyst.
Trifluorothymine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 389)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SURVIVAL TECHNOLOGIES LIMITED | +91 8108285261 | Gujarat, India | 294 | 58 | Inquiry |
| aSai Vishwa Speciality Chemicals Pvt Ltd | +91-2241276501 +91-9920410867 | Maharashtra, India | 58 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group) | 91-22-42361111 | Maharashtra, India | 147 | 58 | Inquiry |
| Survival Technologies Pvt., Ltd. (STPL) | 91-22-61902008 | Maharashtra, India | 119 | 58 | Inquiry |
| Oceanic Pharmachem Pvt., Ltd. (OPPL) | 91-22-42128600 | Maharashtra, India | 946 | 58 | Inquiry |
| Telangana Pharmatech | 08066085722Ext 877 | Hyderabad, India | 34 | 58 | Inquiry |
54-20-6(Trifluorothymine)Related Search:
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3-（trifluoromethyl) Cinnamaldehyde
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2-Methylbenzotrifluoride
[2-13C,15N2]-Trifluorothymine
Trifluridine Impurity
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5-TRIFLUOROMETHYL-1H-PYRIMIDIN-2,4-DIONE
5-(TRIFLUOROMETHYL)URACIL: 98.5%
5-(Trifluoromethyl)uracil,99%
5-TRIFLUORMETHYL-URACIL
1,3,6-trifluoro-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione
2,4(1H,3H)-PyriMidinedione,5-(trifluoroMethyl)-
5-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione, 2,4-Dioxo-1,2,3,4-tetrahydro-5-(trifluoromethyl)pyrimidine
5-Trifluoromethyluracil≥ 98% (HPLC)
TRIFLUOROTHYMINE
1,2,3,4-Tetrahydropyrazin-2,4-dione, 5-trifluoromethyl-
3h)-pyrimidinedione,5-(trifluoromethyl)-4(1h
5-(Trifluoromethyl)-2,4(1H,3H)-pyrimidinedione
5-(trifluoromethyl)-uraci
L 595725-0-1
Uracil, 5-(trifluoromethyl)-
5-(Trifluoromethyl)uracil98%
Trifluorothymine###2,4-Dichloro-5-trichloromethylpyrimidine
5-(trifluoromethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
TRIFLUOROMETHYLURACIL CRYSTALLINE
5-(Trifluoromethyl)uracil,97%
TRIFLUOROTHYMINE(RS20000094)
5-Trifluorothymine
Trifluorothymine 5-
ifluoromethyl)pyrimidine-2,4(1H,3H)-dione
Trifluorothymine-13C4-15N2
Trifluorothymine,54-20-6
5-(Trifluoromethyl)pyrimidine-2,4(1H,3H)-dione
5-(TRIFLUOROMETHYL)URACIL
TRIFLUOROMETHYLURACIL
5-(trifluoroMethyl)pyriMidine-2,4-diol
5-Trifluoromethyl
2,4-DIHYDROXY-5-TRIFLUOROMETHYL-1H-PYRIMIDINE
5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (5-(trifluoromethyl)uracil
5-TRIFLUOROMETHYLURACIL
Trifluorothymine
54-20-6
Pyrimidines
Heterocyclic Building Blocks
Building Blocks
Pyrimidine
Pyrimidines
Miscellaneous
Pyrimidine series
Indolines ,Indoles ,Indazoles
54-20-6