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Cefpimizole

CAS No.: 84880-03-5

Chemical Name:: Cefpimizole

Synonyms: A-1370;U 63196;Cefpimizol;CEFPIMIZOLE;Cefpimizole USP/EP/BP;1-[[(6R)-2-Carboxylato-7α-[[(R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)pyridinium;Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt;Pyridinium,1-[[(6R,7R)-2-carboxy-7-[[(2R)-2-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-,inner salt;(6R,7R)-7-[[(2R)-2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenylacetyl]amino]-8-oxo-3-[[4-(2-sulfonatoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Pyridinium, 1-[[2-carboxy-7-[[[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, [6R-[6α,7β(R*)]]-

CBNumber:: CB9314975

Molecular Formula:: C28H26N6O10S2

Molecular Weight:: 670.67

MOL File:: 84880-03-5.mol

MSDS File:: SDS

Modify Date:: 2023/5/4 17:34:43

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Cefpimizole Chemical Properties,Uses,Production

Description

Cefpimizole sodium is a third-generation cephalosporin with a spectrum of activity somewhat narrower than cefotaxime and cefoperazone.

Uses

Antibacterial.

Antimicrobial activity

A semisynthetic parenteral cephalosporin. It exhibits modest activity compared to other antipseudomonal cephalosporins. Like cefoperazone, it is susceptible to many enterobacterial β-lactamases. In volunteers receiving 0.1–1 g intramuscularly, mean peak plasma concentrations reached 15–20 and 35–40 mg/L, respectively. There was no accumulation when the dose was repeated every 8 h for 7 days. No metabolites have been detected. The plasma elimination half-life is 1.8– 2.1 h. The principal route of elimination is renal, 70–80% being recovered unchanged in the urine.
Significant pain at the site of infection has been a prominent adverse event. It is no longer widely available.

Cefpimizole Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Dicarboxylic Acid cefaloglycin Thionyl chloride

Preparation Products

Cefpimizole Suppliers

Global( 31)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	China	9030	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	26216	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49739	58	Inquiry
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	027-88013699 17354350817	China	7432	58	Inquiry
Zhejiang Huida Biotech Co., LTD	0571-0571-89903882 15990081639	China	3705	58	Inquiry
BOC Sciences	1-631-485-4226; 16314854226	United States	14059	65	Inquiry
Leawell International Limited	020-8768-7760	China	505	56	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
CONIER CHEM AND PHARMA LIMITED	58
TargetMol Chemicals Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58
Dideu Industries Group Limited	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	58
Zhejiang Huida Biotech Co., LTD	58
BOC Sciences	65
Leawell International Limited	56

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Pyridinium, 1-[[(6R,7R)-2-carboxy-7-[[(2R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt Pyridinium, 1-[[2-carboxy-7-[[[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-, inner salt, [6R-[6α,7β(R*)]]- U 63196 (6R,7R)-7-[[(2R)-2-[(5-carboxy-1H-imidazole-4-carbonyl)amino]-2-phenylacetyl]amino]-8-oxo-3-[[4-(2-sulfonatoethyl)pyridin-1-ium-1-yl]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid CEFPIMIZOLE 1-[[(6R)-2-Carboxylato-7α-[[(R)-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)pyridinium Cefpimizol cefpimizole:(6r,7r)-7-(((2r)-2-((5-carboxy-1h-IMIDAZOLE-4-carbonyl)amino)-2-phenylacetyl)amino)-8-oxo-3-((4-(2-sulfonatoethyl)pyridin-1-ium-1-yl)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxyli Cefpimizole USP/EP/BP A-1370 Pyridinium,1-[[(6R,7R)-2-carboxy-7-[[(2R)-2-[[(5-carboxy-1H-imidazol-4-yl)carbonyl]amino]-2-phenylacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-4-(2-sulfoethyl)-,inner salt 84880-03-5 C28H26N6O10S2