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2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide

2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide

CAS:
108605-62-5
MF:
C12H9F3N2O2
MW:
270.21

Properties

Melting point:
229-232°C
Boiling point:
410.8±45.0 °C(Predicted)
Density 
1.424±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
form 
Solid
pka
5.20±0.50(Predicted)
color 
White
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS) 

GHS06
Signal word 
Danger
Hazard statements 
H301
Precautionary statements 
P264-P270-P301+P310-P405-P501
Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2926900005
Toxicity
mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),United States Patent Document. Vol. #5494911,

Use

The active metabolite of Leflunomide, 2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide can be used as a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis.

22 India supplier list of "2-Cyano-3-hydroxy-N-(4'-trifluoromethylphenyl)-crotone amide"

  • Product Name:Teriflunomide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Hyderabad,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Karnataka,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Mumbai,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Gujarat,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Teriflunomide
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA

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