Orotic acid manufacturers and suppliers in india

Orotic acid

Properties

Melting point:: ≥300 °C

Boiling point:: 280.29°C (rough estimate)

Density: 1.6814 (rough estimate)

refractive index: 1.4800 (estimate)

storage temp.: Sealed in dry,Room Temperature

solubility: DMSO : 32 mg/mL (205.00 mM; Need ultrasonic and warming)

pka: pK1:1.8(+1);pK2:9.55(0) (25°C)

form: Crystalline Powder

color: White

Water Solubility: Slightly soluble

Merck: 13,6942

BRN: 383901

Stability:: Stable. Incompatible with strong oxidizing agents.

InChIKey: PXQPEWDEAKTCGB-UHFFFAOYSA-N

LogP: -0.830

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P301+P312+P330-P302+P352-P305+P351+P338

Hazard Codes: Xn,Xi

Risk Statements: 22-36/37/38

Safety Statements: 26-36/37/39-22-37/39

WGK Germany: 3

RTECS: RM3180000

F: 10-21

Hazard Note: Harmful

TSCA: Yes

HS Code: 29335990

Toxicity: pic-esc 1 g/L ZAPOAK12,583,72

Use

Orotic acid (also known as pyrimidinecarboxylic acid) is a heterocyclic acid; it is also known as. Historically it was believed to be part of the vitamin B complex and was called vitamin B13, but it is now known that it is not a vitamin. It is well known as a precursor in biosynthesis of pyrimidines; in mammals it is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. OA is also a normal part of the diet, being found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.