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Lamivudine

Lamivudine

CAS:
134678-17-4
MF:
C8H11N3O3S
MW:
229.26

Properties

Melting point:
177 °C
Boiling point:
475.4±55.0 °C(Predicted)
alpha 
D21 -135° (c = 0.38 in methanol)
Density 
1.73±0.1 g/cm3(Predicted)
refractive index 
-142 ° (C=1, MeOH)
Flash point:
9℃
storage temp. 
2-8°C
solubility 
water: soluble10mg/mL, clear
pka
13.83±0.10(Predicted)
form 
powder
color 
white to beige
Water Solubility 
70g/L(temperature not stated)
Merck 
14,5352
BCS Class
1,3
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey
JTEGQNOMFQHVDC-NKWVEPMBSA-N

Safety Information

Symbol(GHS) 

GHS08
Signal word 
Warning
Hazard statements 
H361
Precautionary statements 
P280
Risk Statements 
63-36/37/38
Safety Statements 
26-36
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
RTECS 
UW7361333
HS Code 
29349990

Use

Lamivudine is the (–) enantiomer of a cytidine analogue with sulfur substituted for the 3'carbon atom in the furanose ring [(–) 2',3'-dideoxy, 3'-thiacytidine]. It has significant activity in vitro against both HIV-1 and HIV-2 as well as HBV. Lamivudine is phosphorylated to the triphosphate metabolite by cellular kinases. The triphosphate derivative is a competitive inhibitor of the viral reverse transcriptase.

119 India supplier list of "Lamivudine"

  • Product Name:Lamivudine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Hyderabad,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Gujarat,INDIA
  • Product Name:Lamivudine
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Telangana,INDIA

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