Telithromycin
Telithromycin
- CAS:
- 191114-48-4
- MF:
- C43H65N5O10
- MW:
- 812
Suppliers by country/region
Company Type
Properties
- Melting point:
- 176-188 C
- Boiling point:
- 966℃
- Density
- 1.26±0.1 g/cm3(Predicted)
- RTECS
- KF4674500
- Flash point:
- >110°(230°F)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- pka
- 10.85±0.70(Predicted)
- form
- Solid
- color
- White to Light Beige
- Water Solubility
- Sparingly soluble in water
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H315-H319-H335-H400-H410
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- HazardClass
- 9
Use
Telithromycin (Ketek) is an orally bioavailable macrolide.The antibiotic is semisynthetic. Telithromycin is classifiedas a ketolide, and it differs chemically from the macrolidegroup of antibacterials by the lack of α-L-cladinose at 3-position of the erythronolide A ring, resulting in a 3-ketofunction. It is further characterized by imidazolyl andpyridyl rings inked to the macrolide nucleus through a butylchain. The mechanism of action of telithromycin is the sameas that of the macrolide class.Telithromycin causes a blockade of protein synthesis bybinding to domains II and V of 23S rRNA of the 50S ribosomalsubunit. Because telithromycin binds at domain II,activity against Gram-positive cocci is retained in the presenceof resistance mediated by methylases that alter thedomain V binding site. The antibiotic is also believed to inhibitthe assembly of ribosomes. Resistance to telithromycinoccurs because of riboprotein mutations.
3 India supplier list of "Telithromycin"
- Product Name:Telithromycin
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Karnataka,INDIA
- Product Name:Telithromycin 95% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.038483
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Telithromycin
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Telithromycin90%
- Products Intro:Brand:clearsynth | Product Number:CS-T-61627
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Telithromycin
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Imidodisulfurylchloride
- Products Intro:Purity: 85.0-99.8% | Package: 1KG;USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Telithromycin
- Products Intro:Purity: >98% | CustNote: BOC Sciences also provides custom synthesis services for Telithromycin.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:telithromycin
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Telithromycin USP/EP/BP
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:TELITHROMYCIN
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes