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diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate

diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate Structure
  • ₹0
  • Product name: diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate
  • CAS: 120533-76-8
  • MF: C24H25NO4
  • MW: 391.46
  • EINECS:-0
  • MDL Number:
  • Synonyms:diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate;DI ETHYL 1 BENZYL 4 PHENYL 4H PYRIDINE 3-5 DICARBOXYLATE;Diethyl 1-benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate;BML-278;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-phenyl-1-(phenylmethyl)-, 3,5-diethyl ester;BML278|||BML 278
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :139-141 °C(Solv: cyclohexane (110-82-7); benzene (71-43-2))
Boiling point :525.5±50.0 °C(Predicted)
Density :1.183±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
pka :2.05±0.70(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BML-278 (120533-76-8) is a structurally novel activator of SIRT1 (EC50=1 μM). Displays selectivity over SIRT2 and 3 (EC50=25 and 50 μM respectively). Cell permeable.

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