18β-Glycyrrhetinic Acid
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- ₹2300 - ₹19052
- Product name: 18β-Glycyrrhetinic Acid
- CAS: 471-53-4
- MF: C30H46O4
- MW: 470.69
- EINECS:207-444-6
- MDL Number:MFCD00003706
- Synonyms:Enoxolone, 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid;Aloe Vera, Freeze Dried Powder;18-β-Glycyrrhetinic acid, 98+%;18-beta-glycyrrheticacid ;Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3b,20b)-;(20S)-3β-Hydroxy-11-oxo-5α-olean-12-en-29-oic acid;GLYCYRRHETINIC ACID, 18B-(P);Glycyrrhetinic acid ,98%
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 1G
- 10G
- 25G
- ManufacturerTCI Chemicals (India)
- Product numberG0149
- Product descriptionGlycyrrhetic Acid
- Packaging1G
- Price₹2300
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberG0149
- Product descriptionGlycyrrhetic Acid
- Packaging25G
- Price₹10700
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG10105
- Product description18β-Glycyrrhetinic acid 97%
- Packaging10G
- Price₹15458.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberG10105
- Product description18β-Glycyrrhetinic acid 97%
- Packaging25G
- Price₹19052
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | G0149 | Glycyrrhetic Acid | 1G | ₹2300 | 2022-05-26 | Buy |
TCI Chemicals (India) | G0149 | Glycyrrhetic Acid | 25G | ₹10700 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | G10105 | 18β-Glycyrrhetinic acid 97% | 10G | ₹15458.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | G10105 | 18β-Glycyrrhetinic acid 97% | 25G | ₹19052 | 2022-06-14 | Buy |
Properties
Melting point :292-295 °C(lit.)
alpha :165 º (c=1, CHCl3,on dry ba)
Boiling point :492.11°C (rough estimate)
Density :0.9967 (rough estimate)
vapor pressure :10-220Pa at 20-50℃
refractive index :162 ° (C=1, MeOH)
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.
pka :pKa 5.56±0.1 (Uncertain)
form :Crystalline Powder
color :White to off-white
optical activity :[α]22/D +170.0°, c = 1 in chloroform
Water Solubility :SOLUBLE IN ACETIC ACID
Merck :14,3590
BRN :2229654
LogP :4.5 at 20℃
CAS DataBase Reference :471-53-4(CAS DataBase Reference)
EPA Substance Registry System :Enoxolone (471-53-4)
alpha :165 º (c=1, CHCl3,on dry ba)
Boiling point :492.11°C (rough estimate)
Density :0.9967 (rough estimate)
vapor pressure :10-220Pa at 20-50℃
refractive index :162 ° (C=1, MeOH)
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.
pka :pKa 5.56±0.1 (Uncertain)
form :Crystalline Powder
color :White to off-white
optical activity :[α]22/D +170.0°, c = 1 in chloroform
Water Solubility :SOLUBLE IN ACETIC ACID
Merck :14,3590
BRN :2229654
LogP :4.5 at 20℃
CAS DataBase Reference :471-53-4(CAS DataBase Reference)
EPA Substance Registry System :Enoxolone (471-53-4)
Safety Information
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Description
β-Glycyrrhetinic acid is a major metabolite of glycyrrhizin, one of the main constituents of licorice. Both β-glycyrrhetinic acid and glycyrrhizin have been shown to exhibit antiulcerative, anti-inflammatory, and immunomodulatory properties. β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC50 = 35 μM). At 100 mg/kg/day, β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. β-Glycyrrhetinic acid inhibits mammalian DNA polymerases α, γ, κ, and λ with IC50 values of 16.1, 19.3, 15.8, and 13.7 μM, respectively. At 100-200 μM, β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.Related product price
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