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2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE

2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE Structure
  • ₹9490 - ₹34619.99
  • Product name: 2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE
  • CAS: 199986-75-9
  • MF: C20H28N6O3
  • MW: 400.47
  • EINECS:
  • MDL Number:MFCD06411412
  • Synonyms:CVT-313;CDK2 INHIBITOR III;2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE;Anti-ABHD16A antibody produced in rabbit;BAT5;D6S82E;2,2'-(9-isopropyl-6-(4-methoxybenzylamino)-9H-purin-2-ylazanediyl)diethanol;CVT-313(NG-26)
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number238803
  • Product descriptionCdk2 Inhibitor III - CAS 199986-75-9 - Calbiochem The Cdk2 Inhibitor III, also referenced under CAS 199986-75-9, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily us
  • Packaging5MG
  • Price₹34619.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number238803
  • Product descriptionCdk2 Inhibitor III - CAS 199986-75-9 - Calbiochem The Cdk2 Inhibitor III, also referenced under CAS 199986-75-9, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily us
  • Packaging1MG
  • Price₹9490
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 238803 Cdk2 Inhibitor III - CAS 199986-75-9 - Calbiochem The Cdk2 Inhibitor III, also referenced under CAS 199986-75-9, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily us 5MG ₹34619.99 2022-06-14 Buy
Sigma-Aldrich(India) 238803 Cdk2 Inhibitor III - CAS 199986-75-9 - Calbiochem The Cdk2 Inhibitor III, also referenced under CAS 199986-75-9, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily us 1MG ₹9490 2022-06-14 Buy

Properties

Boiling point :652.3±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥20 mg/mL in DMSO; insoluble in H2O; ≥51.1 mg/mL in EtOH with gentle warming
pka :13.95±0.10(Predicted)
form :White solid
color :White to off-white
biological source :rabbit
InChIKey :NQVIIUBWMBHLOZ-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

CVT-313 is a cell-permeable purine analog that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk2 (IC50 = 0.5 M for Cdk2/A and Cdk2/E; 4.2 M for Cdk1/B; 215 M for Cdk4/D1). It inhibits other kinases only at much higher concentrations.

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