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OLOMOUCINE II

OLOMOUCINE II Structure
  • ₹28660
  • Product name: OLOMOUCINE II
  • CAS: 500735-47-7
  • MF: C19H26N6O2
  • MW: 370.45
  • EINECS:
  • MDL Number:MFCD06411574
  • Synonyms:Nsc736738;Olomoucine ii, 6-[(2-hydroxybenzyl)amino]-2-[1-(hydroxymethyl)propylamino]- 9-isopropylpurine;2-[[[2-[[(1R)-1-(Hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]phenol;Olomoucine II - CAS 500735-47-7 - Calbiochem;Phenol, 2-[[[2-[[(1R)-1-(hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]-
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Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number495621
  • Product descriptionOlomoucine II - CAS 500735-47-7 - Calbiochem A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B.
  • Packaging5MG
  • Price₹28660
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 495621 Olomoucine II - CAS 500735-47-7 - Calbiochem A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B. 5MG ₹28660 2022-06-14 Buy

Properties

Boiling point :618.5±65.0 °C(Predicted)
Density :1.32
storage temp. :−20°C
solubility :chloroform: 50 mg/mL, soluble
form :powder
pka :9.83±0.30(Predicted)

Safety Information

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Description

Olomoucine II is a selective inhibitor of Cdk1(CDK1)/cyclin B (IC50 = 20 nM). Olomoucine II is a potent cytotoxin in tumor cells: IC50 = 5.3 μM against MCF7 cells, IC50 = 11.1 μM against K562 cells, IC50 = 3.0 μM against CEM cells, IC50 = 6.3 μM against HOS cells, and IC50 = 6.3 μM against G361 cells.

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