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(3β,24S)-Cholest-5-ene-3,24-diol

(3β,24S)-Cholest-5-ene-3,24-diol Structure
  • ₹13628.68 - ₹55077.6
  • Product name: (3β,24S)-Cholest-5-ene-3,24-diol
  • CAS: 474-73-7
  • MF: C27H46O2
  • MW: 402.65
  • EINECS:
  • MDL Number:MFCD03695560
  • Synonyms:(3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4S)-4-hydroxy-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;24-hydroxycholesterol ;cholest-5-ene-3-beta,24-diol;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;cholest-5-ene-3β,24(S)-diol;CHOLEST-5-ENE-3Β,24(S)-DIOL;24(S)-HYDROXYCHOLESTEROL;(24S)-24-hydroxycholesterol;24(S)-HYDROXYCHOLESTEROL
Price2 Properties Safety Information Description
2 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1648
  • Product description24(S)-Hydroxycholesterol ≥98% (HPLC)
  • Packaging1MG
  • Price₹13628.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1648
  • Product description24(S)-Hydroxycholesterol ≥98% (HPLC)
  • Packaging5MG
  • Price₹55077.6
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1648 24(S)-Hydroxycholesterol ≥98% (HPLC) 1MG ₹13628.68 2022-06-14 Buy
Sigma-Aldrich(India) SML1648 24(S)-Hydroxycholesterol ≥98% (HPLC) 5MG ₹55077.6 2022-06-14 Buy

Properties

Melting point :174-176 °C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
form :powder
pka :15.03±0.70(Predicted)
color :white to beige
optical activity :[α]/D -45 to -52°, c = 1 in chloroform-d
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that has important roles in cholesterol homeostasis. It is generated by the action of CYP46 on cholesterol in the brain and diffuses across the blood-brain barrier to the systemic circulation where it can modulate cell signaling, be used for further sterol biosynthesis, or be metabolized in the liver. 24(S)-hydroxy cholesterol potently activates LXRα and LXRβ nuclear receptors (EC50 = 4 and 3 μM, respectively), causing upregulation of cholesterol-lowering genes. In the brain, this oxysterol controls cholesterol processing to facilitate neurological repair during Alzheimer’s disease and other neuropathological conditions.

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Suppliers and manufacturers

Shaanxi Dideu Medichem Co. Ltd
(3β,24S)-Cholest-5-ene-3,24-diol
₹1.00 /1KG
(3β,24S)-Cholest-5-ene-3,24-diol CAS:474-73-7
CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd
Labnetwork lnc.
LEAPCHEM CO., LTD.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific RD International Technology Co., Limited SHANGHAI ZZBIO CO., LTD. Guangzhou Younan Technology Co., Ltd