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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Alkylating antineoplastic >Triethylenethiophosphoramide

Triethylenethiophosphoramide

Triethylenethiophosphoramide Structure
  • ₹25969.18
  • Product name: Triethylenethiophosphoramide
  • CAS: 52-24-4
  • MF: C6H12N3PS
  • MW: 189.22
  • EINECS:200-135-7
  • MDL Number:MFCD00145452
  • Synonyms:triaziridinylphosphinesulfide ;triethylenethiophosphorotriamide ;tris(1-aziridinyl)-phosphinesulfid ;tris(1-aziridinyl)phosphinesulphide ;tris(ethylenimino)thiophosphate ;wr-45312 ;Triethylenethiophosphoramide, 98+%;Thiofosyl
Price1 Properties Safety Information Description
1 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product numberT6069
  • Product descriptionThio-TEPA 97.0-102.0%
  • Packaging1G
  • Price₹25969.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) T6069 Thio-TEPA 97.0-102.0% 1G ₹25969.18 2022-06-14 Buy

Properties

Melting point :54-57 °C
Boiling point :270.2±23.0 °C(Predicted)
Density :1.50±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in benzene, acetone and methanol.
pka :2.74±0.20(Predicted)
form :solid
color :white
Water Solubility :19 g/100 mL (25 ºC)
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :FOCVUCIESVLUNU-UHFFFAOYSA-N
CAS DataBase Reference :52-24-4
IARC :1 (Vol. Sup 7, 50, 100A) 2012
NIST Chemistry Reference :Thiotepa(52-24-4)
EPA Substance Registry System :Thiotepa (52-24-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Tri(1-aziridinyl)phosphine sulfide is useful for the treatment of cancers, especially cancers resistant to chemotherapy. Antineoplastic. Thio-TEPA (N,N?N?-triethylenethiophosphoramide) is used as a cancer chemotherapeutic, alkylating agent. It is used to treat various kinds of cancer such as breast, ovarian and bladder cancer. It is also used as conditioning treatment prior to hematopoietic progenitor cell transplantation (HPCT)

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Suppliers and manufacturers

Basil Drugs AND Pharmaceuticals Pvt Ltd NATCO Pharma Limited Mylan Laboratories Ltd Aspen Biopharma Labs Pvt Ltd MSN LABORATORIES PRIVATE LTD EMCURE PHARMACEUTICALS LTD Pharmaffiliates Analytics and Synthetics P. Ltd SynZeal Research Pvt Ltd Shri Swami Samarth Surgicals CLEARSYNTH LABS LTD.