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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Ethylpyridine >4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-

4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-

4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]- Structure
  • ₹0
  • Product name: 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-
  • CAS: 663619-89-4
  • MF: C21H24N4O2
  • MW: 364.44
  • EINECS:
  • MDL Number:MFCD11113209
  • Synonyms:4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-;TGX 221;(+/-)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one;7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one;(+/-)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one TGX 221;TGX 221 (+/-)-7-Methyl-2-(morpholin-4-yl)-9-(1-phenylaminoethyl)pyrido[1,2-a]pyrimidin-4-one;PI 3-Kβ Inhibitor VI, TGX-221;CS-429
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :198-201oC
Boiling point :557.3±60.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :DMSO (Slightly), Methanol (Very Slightly)
pka :3.90±0.50(Predicted)
form :Pale yellow solid.
color :Off-White to Pale Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

PI 3-Kβ Inhibitor VI, TGX-221 is a cell-permeable morpholino-pyrimidinone compound that acts as a reversible, ATP-competitive, selective, and highly potent inhibitor of PI 3-kinase β (IC50 = 0.005, 0.1, 5, and ≥3.5 M for -β, -δ, -α and -γ isoforms, respectively) with little activity against a panel of 15 commonly studied protein kinases even at concentrations as high as 10.0 M. PI 3-Kβ Inhibitor VI, TGX-221 is an excellent tool for studying p110b-dependent responses in cells in vitro.

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Suppliers and manufacturers

career henan chemical co
4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-
₹2.00 /1kg
4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]- CAS:663619-89-4
Shaanxi Dideu Medichem Co. Ltd
4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]-
₹1.10 /1g
4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]- CAS:663619-89-4
A.J Chemicals CLEARSYNTH LABS LTD.
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.