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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Leucine derivatives >(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE

(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE

(L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE Structure
  • ₹4869 - ₹124141.1
  • Product name: (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCYLAGMATINE HEMIHYDRATE
  • CAS: 66701-25-5
  • MF: C15H27N5O5
  • MW: 357.41
  • EINECS:613-978-4
  • MDL Number:MFCD07366493
  • Synonyms:(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid;(2S,3S)-3-(((S)-1-((4-Guanidinobutyl)amino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carb;oxiranecarboxylicacid,3-(((1-(((4-((aminoiminomethyl)amino)butyl)amino)carbon ;proteinaseinhibitore64 ;thiolproteaseinhibitor ;TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-*(4-GU ANIDINO)BUT;(2S, 3S)-TRANS-EPOXY SUCCINYL-L-LEUCYLAMIDO-(4-GUANIDINO) BUTANE;L-TRANS-3-CARBOXYOXIRAN-2-CARBONYL-L-LEUCYLAGMATINE
11 prices
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Brand

  • ALFA India
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 1MG
  • 5mg
  • 10MG
  • 25mg
  • 50MG
  • ManufacturerALFA India
  • Product numberALF-J62933-LB0
  • Product descriptionE-64
  • Packaging5mg
  • Price₹7074
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J62933-MB
  • Product descriptionE-64
  • Packaging25mg
  • Price₹62934
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE3132
  • Product descriptionE-64 protease inhibitor
  • Packaging1MG
  • Price₹7252.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE3132
  • Product descriptionE-64 protease inhibitor
  • Packaging5MG
  • Price₹22656.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE3132
  • Product descriptionE-64 protease inhibitor
  • Packaging10MG
  • Price₹36837.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE3132
  • Product descriptionE-64 protease inhibitor
  • Packaging25MG
  • Price₹69388.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE3132
  • Product descriptionE-64 protease inhibitor
  • Packaging50MG
  • Price₹124141.1
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number E 5550
  • Product descriptionE-64, protease inhibitor
  • Packaging1mg
  • Price₹4869
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number E 5550
  • Product descriptionE-64, protease inhibitor
  • Packaging5mg
  • Price₹15039
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number E 5550
  • Product descriptionE-64, protease inhibitor
  • Packaging10mg
  • Price₹24003
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number E 5550
  • Product descriptionE-64, protease inhibitor
  • Packaging25mg
  • Price₹46089
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J62933-LB0 E-64 5mg ₹7074 2022-05-26 Buy
ALFA India ALF-J62933-MB E-64 25mg ₹62934 2022-05-26 Buy
Sigma-Aldrich(India) E3132 E-64 protease inhibitor 1MG ₹7252.75 2022-06-14 Buy
Sigma-Aldrich(India) E3132 E-64 protease inhibitor 5MG ₹22656.73 2022-06-14 Buy
Sigma-Aldrich(India) E3132 E-64 protease inhibitor 10MG ₹36837.48 2022-06-14 Buy
Sigma-Aldrich(India) E3132 E-64 protease inhibitor 25MG ₹69388.25 2022-06-14 Buy
Sigma-Aldrich(India) E3132 E-64 protease inhibitor 50MG ₹124141.1 2022-06-14 Buy
ottokemi E 5550 E-64, protease inhibitor 1mg ₹4869 2022-05-26 Buy
ottokemi E 5550 E-64, protease inhibitor 5mg ₹15039 2022-05-26 Buy
ottokemi E 5550 E-64, protease inhibitor 10mg ₹24003 2022-05-26 Buy
ottokemi E 5550 E-64, protease inhibitor 25mg ₹46089 2022-05-26 Buy

Properties

Melting point :>170°C (dec.)
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :H2O: 20 mg/mL, clear, colorless
pka :3.16±0.40(Predicted)
form :White solid
color :White or off-white
Water Solubility :Soluble in DMSO (25mg/ml), or water (20mg/ml)
Sensitive :Light Sensitive
BRN :1405664
Stability :Stable for 1 year from date of purchase as supplied.
InChIKey :LTLYEAJONXGNFG-DCAQKATOSA-N
SMILES :O1[C@H](C(N[C@H](C(NCCCCNC(N)=N)=O)CC(C)C)=O)[C@H]1C(O)=O
CAS DataBase Reference :66701-25-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

It is used as a broad spectrum cysteine proteinase and calpain activation inhibitor. Additionally, Prevotella intermediate studies report that E-64 blocks the breakdown of methaemoglobin and the oxidation of oxyhaemoglobin by InpA. E-64 has also been used to study excystation in Giardia lamblia. E-64 is an inhibitor of Calpain, cathepsin K and cathepsin S. E-64 is an effective ligand for affinity purification of cysteine proteases. When coupled to a thiolated affinity matrix, binding is no longer irreversible, but specificity is retained

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