Mitoxantrone hydrochloride
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- ₹4400 - ₹18012.8
- Product name: Mitoxantrone hydrochloride
- CAS: 70476-82-3
- MF: C22H30Cl2N4O6
- MW: 517.4028
- EINECS:274-619-1
- MDL Number:MFCD00242943
- Synonyms:1,4-dihydroxy-5,8-bis(2-(2-hydroxyethylamino)ethylamino)anthracene-9,10-dione dihydrochloride;Mitoxantrone hydrochloride 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride;Mitoxantrone dihydrochloride, >=99%;MITOXANTRONE HYDROCHLORIDE;MITOXANTRONE HYDROCHLORIDE SALT;MITOXANTHRONE HCL;mitozantrone hydrochloride;DHAQ DIHYDROCHLORIDE
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 25MG
- 50MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberM3110
- Product descriptionMitoxantrone Dihydrochloride
- Packaging25MG
- Price₹4400
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM3110
- Product descriptionMitoxantrone Dihydrochloride
- Packaging100MG
- Price₹9900
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM6545
- Product descriptionMitoxantrone dihydrochloride ≥97% (HPLC)
- Packaging10MG
- Price₹5910.45
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM6545
- Product descriptionMitoxantrone dihydrochloride ≥97% (HPLC)
- Packaging50MG
- Price₹18012.8
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | M3110 | Mitoxantrone Dihydrochloride | 25MG | ₹4400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M3110 | Mitoxantrone Dihydrochloride | 100MG | ₹9900 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | M6545 | Mitoxantrone dihydrochloride ≥97% (HPLC) | 10MG | ₹5910.45 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M6545 | Mitoxantrone dihydrochloride ≥97% (HPLC) | 50MG | ₹18012.8 | 2022-06-14 | Buy |
Properties
Melting point :203-205 C
storage temp. :2-8°C
solubility :Sparingly soluble in water, slightly soluble in methanol, practically insoluble in acetone.
form :Solid
color :Dark Blue to Black
Water Solubility :Soluble to 5 mM in water and to 75 mM in DMSO
InChI :InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
InChIKey :ZAHQPTJLOCWVPG-UHFFFAOYSA-N
SMILES :C1(O)=C2C(C(=O)C3=C(C2=O)C(NCCNCCO)=CC=C3NCCNCCO)=C(O)C=C1.[H]Cl.[H]Cl
CAS DataBase Reference :70476-82-3(CAS DataBase Reference)
EPA Substance Registry System :Mitoxantrone hydrochloride (70476-82-3)
storage temp. :2-8°C
solubility :Sparingly soluble in water, slightly soluble in methanol, practically insoluble in acetone.
form :Solid
color :Dark Blue to Black
Water Solubility :Soluble to 5 mM in water and to 75 mM in DMSO
InChI :InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
InChIKey :ZAHQPTJLOCWVPG-UHFFFAOYSA-N
SMILES :C1(O)=C2C(C(=O)C3=C(C2=O)C(NCCNCCO)=CC=C3NCCNCCO)=C(O)C=C1.[H]Cl.[H]Cl
CAS DataBase Reference :70476-82-3(CAS DataBase Reference)
EPA Substance Registry System :Mitoxantrone hydrochloride (70476-82-3)
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein -1. This compound has found use in various forms of cancer and in multiple sclerosis.More related product prices
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