Welcome to chemicalbook!
China english Japan Germany India
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
head sculpture My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Transmembrane Transporters >Calcium Channel Inhibitors >Ranolazine dihydrochloride

Ranolazine dihydrochloride

Ranolazine dihydrochloride Structure
  • ₹8700 - ₹86188.65
  • Product name: Ranolazine dihydrochloride
  • CAS: 95635-56-6
  • MF: C24H35Cl2N3O4
  • MW: 500.46
  • EINECS:
  • MDL Number:MFCD03788770
  • Synonyms:(+/-)-4-[2-HYDROXY-3-(O-METHOXYPHENOXY)PROPYL]-1-PIPERAZINEACETO-2',6'-XYLIDIDE DIHYDROCHLORIDE;n-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide dihydrochloride;(+/-)-N-(2,6-DIMETHYLPHENYL)-4-[2-HYDROXY-3-(2-METHOXYPHENOXY)PROPYL]-1-PIPERAZINEACETAMIDE DIHYDROCHLORIDE;RANOLAZINE DIHYDROCHLORIDE;RANOLAZINE HCL;Ranolazine DiHCI ;Ranolazine and salt;N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)-propyl)piperazin-1-yl)acetamide di
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 500MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberR0112
  • Product descriptionRanolazine Dihydrochloride
  • Packaging1G
  • Price₹8700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberR0112
  • Product descriptionRanolazine Dihydrochloride
  • Packaging5G
  • Price₹15600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR6152
  • Product descriptionRanolazine dihydrochloride ≥98% (HPLC), powder
  • Packaging100MG
  • Price₹21541.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberR6152
  • Product descriptionRanolazine dihydrochloride ≥98% (HPLC), powder
  • Packaging500MG
  • Price₹86188.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) R0112 Ranolazine Dihydrochloride 1G ₹8700 2022-05-26 Buy
TCI Chemicals (India) R0112 Ranolazine Dihydrochloride 5G ₹15600 2022-05-26 Buy
Sigma-Aldrich(India) R6152 Ranolazine dihydrochloride ≥98% (HPLC), powder 100MG ₹21541.75 2022-06-14 Buy
Sigma-Aldrich(India) R6152 Ranolazine dihydrochloride ≥98% (HPLC), powder 500MG ₹86188.65 2022-06-14 Buy

Properties

Melting point :222-229.5 °C(lit.)
storage temp. :Desiccate at RT
solubility :H2O: 10 mg/mL, soluble
form :solid
color :off-white
Merck :14,8111
Stability :Hygroscopic
CAS DataBase Reference :95635-56-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Ranolazine was developed to protect the heart from transient ischemia, as may occur during angina and infarct. It has diverse effects at the cellular level, inhibiting late sodium and potassium currents (IC50s = 3.9-16.6 μM for both) and blocking ligand binding to α1, β1, and β2 adrenergic receptors (Kis = 0.5-19.5 μM for all). Ranolazine inhibits fatty acid β-oxidation leading to decreased acetyl CoA, activation of pyruvate dehydrogenase, and increased glucose oxidation. It also weakly inhibits mitochondrial respiratory complex I.

More related product prices

Cetirizine hydrochloride CHLOROPHOSPHONAZO III Thioacetamide Promethazine hydrochloride Ranolazine Propyl butyrate Acetamide Chlorpromazine hydrochloride Propyl gallate N,N-Dimethylacetamide Methoxyammonium chloride Capecitabine Zolmitriptan Glycyrrhizic acid Tenofovir THIFLUZAMIDE Ranolazine dihydrochloride

Related product price

Suppliers and manufacturers

Aarti Industries Limited (AIL) Manus Aktteva A.J Chemicals CLEARSYNTH LABS LTD. TCI Chemicals (India) Pvt. Ltd. A R Life Sciences Private Limited Zydus Cadila (Cadila Healthcare Ltd.) Opulent Pharma Sai Prathyu Marketing Monarch Pharmachem