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AKTI-1/2

AKTI-1/2 Structure
  • ₹20250 - ₹24590.01
  • Product name: AKTI-1/2
  • CAS: 612847-09-3
  • MF: C34H29N7O
  • MW: 551.64
  • EINECS:1592732-453-0
  • MDL Number:MFCD09026909
  • Synonyms:1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-on;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-γ],guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one;1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one;2H-BenziMidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-iMidazo[4,5-g]quinoxalin-7-yl)phenyl]Methyl]-4-piperidinyl]-;AKT inhibitor VIII (AKTI-1/2);1-(1-(4-(6-Phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)-piperidin-4-yl)-1H-benzo[d]imidazol-2(;1-(1-(4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)benzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberA3153
  • Product descriptionAKT Inhibitor VIII
  • Packaging100MG
  • Price₹23000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number124018
  • Product descriptionAkt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12
  • Packaging1MG
  • Price₹20250
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number124018
  • Product descriptionAkt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12
  • Packaging5MG
  • Price₹24590.01
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A3153 AKT Inhibitor VIII 100MG ₹23000 2022-05-26 Buy
Sigma-Aldrich(India) 124018 Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12 1MG ₹20250 2022-06-14 Buy
Sigma-Aldrich(India) 124018 Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 - CAS 612847-09-3 - Calbiochem Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2, CAS 612847-09-3, is a cell-permeable, reversible inhibitor of Akt1/Akt2 (IC?? = 58 nM, 210 nM, & 2.12 5MG ₹24590.01 2022-06-14 Buy

Properties

Melting point :242-245°C (dec.)
Density :1.350±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :insoluble in H2O; insoluble in EtOH; ≥9.2 mg/mL in DMSO
pka :7.49±0.50(Predicted)
form :Yellow solid
color :White to Yellow to Orange
CAS DataBase Reference :612847-09-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBα, β, γ) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 μM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin regulation of forkhead box 01 activity at 1 μM in rat hepatoma cells.

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Suppliers and manufacturers

career henan chemical co
AKTI-1/2
₹2.00 /1kg
AKTI-1/2 CAS:612847-09-3
CLEARSYNTH LABS LTD. TCI Chemicals (India) Pvt. Ltd.
ATK CHEMICAL COMPANY LIMITED
Jinan Carbotang Biotech Co.,Ltd.
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nantong HI-FUTURE Biology Co., Ltd.