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(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE

(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE Structure
  • ₹13100 - ₹40640
  • Product name: (5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE
  • CAS: 404828-08-6
  • MF: C18H19N5
  • MW: 305.38
  • EINECS:
  • MDL Number:MFCD09037536
  • Synonyms:GSK-3 INHIBITOR XIII;(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE;4-Quinazolinamine, 5,6,7,8-tetrahydro-N-(5-methyl-1H-pyrazol-3-yl)-2-phenyl-;GSK3i XIII;Glycogen synthase kinase 3,Glycogen synthase kinase-3,ATP-competitive,GSK3i XIII,Inhibitor,GSK-3 Inhibitor XIII,GSK-3i XIII,GSK-3,inhibit;N-(5-methyl-1H-pyrazol-3-yl)-2-phenyl-5,6,7,8-tetrahydroquinazolin-4-amine
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Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product number361555
  • Product descriptionGSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily
  • Packaging1MG
  • Price₹13100
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number361555
  • Product descriptionGSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily
  • Packaging5MG
  • Price₹40640
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 361555 GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily 1MG ₹13100 2022-06-14 Buy
Sigma-Aldrich(India) 361555 GSK-3 Inhibitor XIII - CAS 404828-08-6 - Calbiochem The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily 5MG ₹40640 2022-06-14 Buy

Properties

Boiling point :451.8±45.0 °C(Predicted)
Density :1.262±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:0.25(Max Conc. mg/mL);0.83(Max Conc. mM)
DMSO:0.15(Max Conc. mg/mL);0.5(Max Conc. mM) form :White crystalline solid.
pka :13.78±0.10(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

GSK-3 Inhibitor XIII is an aminopyrazole compound that acts as an ATP-binding site inhibitor of GSK-3. Studies suggest that GSK-3 is a multifunctional serine/threonine kinase involved in estrogen and androgen receptor stability by phosphorylation. GSK-3 can bind to androgen receptors forming complexes in the cytoplasm and nucleus, so inhibition by GSK-3 Inhibitor XIII, will result in a rapid nuclear export of endogenous androgen receptors thus reducing receptors for the enzyme to bind to.

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