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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >protein tyrosine kinase >Tivozanib

Tivozanib

Tivozanib Structure
  • ₹0
  • Product name: Tivozanib
  • CAS: 475108-18-0
  • MF: C22H19ClN4O5
  • MW: 454.86
  • EINECS:
  • MDL Number:MFCD15146788
  • Synonyms:AV-951;Tivozanib;N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea;AV-951(Tivozanib);1-(2-Chloro-4-(6,7-diMethoxyquinolin-4-yloxy)phenyl)-3-(5-Methylisoxazol-3-yl)urea;TIVOZANIB;AV951;KRN951, TIVOZANIB) (STOPPED USE SINCE THE PATENT ISSUE;N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzaMide
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>202°C (dec.)
Boiling point :550.4±50.0 °C(Predicted)
Density :1.421
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :White powder.
pka :11.74±0.70(Predicted)
color :Pale Beige to Light Brown

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Tivozanib (AV-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 30 nM/6.5 nM/15 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met, EGFR and IGF-1R. Phase 3.

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Related product price

Suppliers and manufacturers

shandong perfect biotechnology co.ltd
Tivozanib
₹0.00 /1g
Tivozanib CAS:475108-18-0
career henan chemical co
N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea
₹1.00 /1kg
N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea CAS: 475108-18-0
SynZeal Research Pvt Ltd CLEARSYNTH LABS LTD. A.J Chemicals
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Chongqing Chemdad Co., Ltd