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ChemicalBook > Product Catalogue >API >Antiparasitic drugs >Antimalarial drugs >Artesunate

Artesunate

Artesunate Structure
  • ₹4300 - ₹50336.25
  • Product name: Artesunate
  • CAS: 88495-63-0
  • MF: C19H28O8
  • MW: 384.42
  • EINECS:618-170-5
  • MDL Number:MFCD00866204
  • Synonyms:Artesunate (3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-ol hydrogen succinate;ARTESUNATE;ArtesunateC19H28O8;Butanedioic Acid Mono(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] Ester;Arteannuinum;Arteannuinum succinate;vARTESUNATE;(3R,5aα,8aα,12aR)-Decahydro-10α-(3-carboxypropionyloxy)-3,6α,9β-trimethyl-3β,12α-epoxypyrano[4,3-j]-1,2-benzodioxepin
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 300MG
  • 500MG
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2191
  • Product descriptionArtesunate
  • Packaging5G
  • Price₹4300
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2191
  • Product descriptionArtesunate
  • Packaging25G
  • Price₹12000
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR2573
  • Product descriptionArtesunate Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging300MG
  • Price₹15847.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA3731
  • Product descriptionArtesunate from Artemisia annua
  • Packaging100MG
  • Price₹29833.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA3731
  • Product descriptionArtesunate from Artemisia annua
  • Packaging500MG
  • Price₹50336.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2191 Artesunate 5G ₹4300 2022-05-26 Buy
TCI Chemicals (India) A2191 Artesunate 25G ₹12000 2022-05-26 Buy
Sigma-Aldrich(India) PHR2573 Artesunate Pharmaceutical Secondary Standard; Certified Reference Material 300MG ₹15847.8 2022-06-14 Buy
Sigma-Aldrich(India) A3731 Artesunate from Artemisia annua 100MG ₹29833.7 2022-06-14 Buy
Sigma-Aldrich(India) A3731 Artesunate from Artemisia annua 500MG ₹50336.25 2022-06-14 Buy

Properties

Melting point :132-1350C
Boiling point :431.1°C (rough estimate)
Density :1.2076 (rough estimate)
refractive index :1.4430 (estimate)
storage temp. :2-8°C
solubility :acetone: soluble33.4mg/mL
form :crystalline powder
pka :4.28±0.17(Predicted)
color :white to off-white
Merck :14,818
BCS Class :3/1
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :FIHJKUPKCHIPAT-AHIGJZGOSA-N
SMILES :C(O[C@@H]1O[C@]2([H])O[C@@]3(C)CC[C@@]4([H])[C@H](C)CC[C@@]([H])([C@H]1C)[C@]42OO3)(=O)CCC(O)=O
LogP :3.291 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Description

Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax (IC50 = 1.3 nM). It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis. Sesquiterpene lactones like artesunate, artemether, and artemisinin have potential applications in certain types of cancer and inflammatory conditions.

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