BISINDOLYLMALEIMIDE VII
|
- ₹10586.85
- Product name: BISINDOLYLMALEIMIDE VII
- CAS: 137592-47-3
- MF: C27H27N5O2
- MW: 453.54
- EINECS:
- MDL Number:MFCD01076634
- Synonyms:BISINDOLYLMALEIMIDE VII;1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[3-(1-piperazinyl)propyl]-1H-indol-3-yl]-
1 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product numberB3681
- Product descriptionBisindolylmaleimide VII 96% (TLC), solid
- Packaging1MG
- Price₹10586.85
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B3681 | Bisindolylmaleimide VII 96% (TLC), solid | 1MG | ₹10586.85 | 2022-06-14 | Buy |
Properties
Boiling point :761.6±60.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: soluble
form :solid
pka :8.18±0.60(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: soluble
form :solid
pka :8.18±0.60(Predicted)
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Bisindolylmaleimides are potent, selective inhibitors of protein kinase C (PKC). They are structurally similar to the naturally occurring molecule, staurosporine, but they are more selective for PKC over other protein kinases. Bisindolylmaleimides are used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals. Bisindolylmaleimides inhibit PKC by interacting with the catalytic subunit. Inhibition is competitive with ATP. Studies of structure-activity relationships of analogs indicate that cationic substituents at the indole nitrogen increase the potency as an inhibitor of PKC.Related product price
- GF109203X
₹4000-88851.6 - D-ERYTHRO-SPHINGOSINE
₹10400-108498.98 - GO 6976
₹22650-26950