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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Proteases >MMP inhibitors >Batimastat

Batimastat

Batimastat Structure
  • ₹12940 - ₹89143.88
  • Product name: Batimastat
  • CAS: 130370-60-4
  • MF: C23H31N3O4S2
  • MW: 477.64
  • EINECS:
  • MDL Number:MFCD00866533
  • Synonyms:Butanediamide, N4-hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-, (2R,3S)-;BB 94;(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide;Batimastat;(2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide;BatiMastat (MMP Inhibitor);N4-hydroxy-N1-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-, (2R,3S)-;(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide Batimastat
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 2MG
  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product number5.08408
  • Product descriptionInSolution Batimastat - CAS 130370-60-4 - Calbiochem
  • Packaging2MG
  • Price₹12940
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number196440
  • Product descriptionBatimastat - CAS 130370-60-4 - Calbiochem Batimastat primarily used in Inhibition.
  • Packaging5MG
  • Price₹13100
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0041
  • Product descriptionBatimastat ≥98% (HPLC)
  • Packaging5MG
  • Price₹22375.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0041
  • Product descriptionBatimastat ≥98% (HPLC)
  • Packaging25MG
  • Price₹89143.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 5.08408 InSolution Batimastat - CAS 130370-60-4 - Calbiochem 2MG ₹12940 2022-06-14 Buy
Sigma-Aldrich(India) 196440 Batimastat - CAS 130370-60-4 - Calbiochem Batimastat primarily used in Inhibition. 5MG ₹13100 2022-06-14 Buy
Sigma-Aldrich(India) SML0041 Batimastat ≥98% (HPLC) 5MG ₹22375.28 2022-06-14 Buy
Sigma-Aldrich(India) SML0041 Batimastat ≥98% (HPLC) 25MG ₹89143.88 2022-06-14 Buy

Properties

Melting point :236-238°
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: ≥15mg/mL
form :powder
pka :9.04±0.40(Predicted)
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :XFILPEOLDIKJHX-QYZOEREBSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Batimastat is a broad spectrum inhibitor of matrix metalloproteinases (MMP), with IC50 values of 1-5 nM for all MMPs tested, including MMP-1, -2, -3, -7, -9, -13, and -14. It also potently inhibits TNFα-converting enzyme (IC50 = 14.9 nM). Because of its action on MMPs, batimastat has anti-proliferative, anti-invasive, and anti-metastatic actions that are relevant, in particular, to cancer. Batimastat less effectively inhibits the processing of the low affinity IgE receptor CD23 (IC50 = 100 nM).

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