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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cell Cycle >Rho inhibitor >CCG-1423

CCG-1423

CCG-1423 Structure
  • ₹8000 - ₹52360.53
  • Product name: CCG-1423
  • CAS: 285986-88-1
  • MF: C18H13ClF6N2O3
  • MW: 454.75
  • EINECS:
  • MDL Number:MFCD01566719
  • Synonyms:CCG-1423;N-(2-(4-Chloroanilino)-1-Methyl-2-oxoethoxy)-3,5-bis(trifluoroMethyl)benzaMide;N-(1-(4-chlorophenylaMino)-1-oxopropan-2-yloxy)-3,5-bis(trifluoroMethyl)benzaMide;N-({1-[(4-Chlorophenyl)Amino]-1-Oxo-2-Propanyl}Oxy)-3,5-Bis(Trifluoromethyl)Benzamide CCG-1423;N-[2-[(4-Chlorophenyl)amino]-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl)-benzamide;N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide;Rho/SRF Pathway Inhibitor, CCG-1423 ;CCG-1423 USP/EP/BP
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC3449
  • Product descriptionCCG-1423
  • Packaging25MG
  • Price₹8000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3449
  • Product descriptionCCG-1423
  • Packaging100MG
  • Price₹21800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0987
  • Product descriptionCCG-1423 ≥98% (HPLC)
  • Packaging5MG
  • Price₹13000.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number555558
  • Product descriptionRho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem The Rho/SRF Pathway Inhibitor, CCG-1423, also referenced under CAS 285986-88-1, controls the biological activity of Rho/SRF. This small molecule/inhib
  • Packaging25MG
  • Price₹16670.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0987
  • Product descriptionCCG-1423 ≥98% (HPLC)
  • Packaging25MG
  • Price₹52360.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3449 CCG-1423 25MG ₹8000 2022-05-26 Buy
TCI Chemicals (India) C3449 CCG-1423 100MG ₹21800 2022-05-26 Buy
Sigma-Aldrich(India) SML0987 CCG-1423 ≥98% (HPLC) 5MG ₹13000.83 2022-06-14 Buy
Sigma-Aldrich(India) 555558 Rho/SRF Pathway Inhibitor, CCG-1423 - CAS 285986-88-1 - Calbiochem The Rho/SRF Pathway Inhibitor, CCG-1423, also referenced under CAS 285986-88-1, controls the biological activity of Rho/SRF. This small molecule/inhib 25MG ₹16670.01 2022-06-14 Buy
Sigma-Aldrich(India) SML0987 CCG-1423 ≥98% (HPLC) 25MG ₹52360.53 2022-06-14 Buy

Properties

storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :White solid
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

CCG-1423 is a specific inhibitor of Rho pathway-mediated signalling and activation of serum response factor (SRF) transcription. The Rho family of small GTPases play a vital role in transduction of cell signalling events associated with several human cancers. It inhibits SRF-driven luciferase expression in PC-3 cells following stimulation with constitutively active Gα13 with an IC50 value of 1 μM. The site of inhibition in the pathway is not precisely defined but CCG-1423 appears to act on some aspect of the interaction of SRF with its transcriptional cofactor megakaryoblastic leukemia 1 (MKL1) at a point upstream of DNA binding. CCG-1423 selectively inhibits DNA synthesis, proliferation and invasion of Rho-overexpressing cell lines at nanomolar to low micromolar concentrations.

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career henan chemical co
N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide
₹1.00 /1KG
N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide CAS:285986-88-1
CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd.
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Zhejiang J&C Biological Technology Co.,Limited