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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antipsychotics >Chlorprothixene

Chlorprothixene

Chlorprothixene Structure
  • ₹3600 - ₹8000
  • Product name: Chlorprothixene
  • CAS: 113-59-7
  • MF: C18H18ClNS
  • MW: 315.86
  • EINECS:204-032-8
  • MDL Number:MFCD00869180
  • Synonyms:(3E)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine;(alpha-2-chloro-9-omega-dimethylamino-propylamine)thioxanthene ;2-chloro-n,n-dimethylthioxanthene-delta(sup9),gamma-propylamine ;2-Chloro-N,N-dimethylthioxanthene-delta9, gamma-propylamine;3-(2-chloro-9H-thioxanthen-9-ylidene)-N-,N-dimethyl-1-propanamine ;3-(2-chloro-9h-thioxanthen-9-ylidene)-n,n-dimethyl-1-propanamine ;9H-Thioxanthene, 1-propanamine deriv.;9H-thioxanthene,1-propanaminederiv.
3 prices
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Brand

  • TCI Chemicals (India)

Package

  • 250MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberC3505
  • Product descriptionChlorprothixene min. 97.0 %
  • Packaging250MG
  • Price₹3600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3505
  • Product descriptionChlorprothixene min. 97.0 %
  • Packaging1G
  • Price₹6000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3505
  • Product descriptionChlorprothixene min. 97.0 %
  • Packaging5G
  • Price₹8000
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3505 Chlorprothixene min. 97.0 % 250MG ₹3600 2022-05-26 Buy
TCI Chemicals (India) C3505 Chlorprothixene min. 97.0 % 1G ₹6000 2022-05-26 Buy
TCI Chemicals (India) C3505 Chlorprothixene min. 97.0 % 5G ₹8000 2022-05-26 Buy

Properties

Melting point :97-98°
Boiling point :160 °C(Press: 0.04 Torr)
Density :1.1048 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO : 33.33 mg/mL (105.52 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :powder to crystal
pka :pKa 8.4(H2O) (Uncertain)
color :White to Orange to Green
Water Solubility :385.8ug/L(22.5 ºC)
Stability :Hygroscopic
NIST Chemistry Reference :Chlorprothixene(113-59-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:

Description

In 2002, the American Association of Poison Control Centers’ Toxic Exposure Surveillance System reported 5224 human exposures to phenothiazines, thioxanthenes, and other neuroleptic medications; 3691 were in adults and 808 in children. Unintentional and intentional exposures accounted for 43.7 and 47.8%, respectively. There were 417 (8.0%) adverse drug reactions reported. Thioxanthenes are chemical compounds in which the oxygen atom in xanthene is replaced with a sulfur atom. They are also related to phenothiazines. Several derivatives are used as typical antipsychotics in the treatment of schizophrenia and other psychoses. The thioxanthenes, as a class, are closely related chemically to the phenothiazines. The major structural difference is that the nitrogen at position 10 in the phenothiazines is replaced by a carbon atom with a double bond to the side chain, as shown in the chemical structure of flupenthixol, which has a double-bonded carbon in the number 10 position. Clopenthixol is a typical antipsychotic drug of the thioxanthenes class and a racemic mixture of cis and trans isomers. Zuclopenthixol, the pure cis isomer, has been much more widely used. Both drugs are equally effective as antipsychotics and have similar adverse effect profiles, but clopenthixol is half as active on a milligram-to-milligram basis and appears to produce more sedation in comparison.

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